68754-17-6

Upstream product

• 26103-97-9 phloroisovalerophenone 
• 108-12-3 isopentanoyl chloride 
• 108-73-6 3,5-dihydroxyphenol 
• 830-79-5 2,4,6-trimethoxybenzaldehyde 
• 167385-77-5 2-(1-Hydroxy-3-methyl-butyl)-3,5-dimethoxy-phenol 
• 68754-16-5 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-methylbutan-1-one 
• 708-76-9 2-hydroxy-4,6-dimethoxybenzaldehyde 

Downstream Products

• 68754-19-8 2,4-Dimethoxy-benzoic acid 3,5-dimethoxy-2-(3-methyl-butyl)-6-(5-methyl-hexanoyl)-phenyl ester 
• 68754-20-1 1-(2,4-Dimethoxy-phenyl)-3-[2-hydroxy-4,6-dimethoxy-3-(3-methyl-butyl)-phenyl]-2-(3-methyl-butyl)-propane-1,3-dione 
• 870681-79-1 (+/-)-8-(3-methylbutyl)-5,7-dimethoxy-4-(4-methoxyphenyl)-3,4-dihydrocoumarin 
• 17245-27-1 3-Isopentyl-4.6-dimethoxy-salicylaldehyd 
• 102662-84-0 5,7-dimethoxy-8-(3-methyl-butyl)-4-phenyl-chromen-2-one 

Relevant academic research and scientific papers

Regioselective synthesis and estrogenicity of (±)-8-alkyl-5,7- dihydroxy-4-(4-hydroxyphenyl)-3,4-dihydrocoumarins

Nine new (±)-8-alkyl-5,7-dihydroxy-4-(4-hydroxyphenyl)-3,4- dihydrocoumarins have been synthesized from 2,4,6-trimethoxybenzaldehyde via a short, efficient, and regioselective pathway, together with the unsubstituted analogue (±)-5,7-dihydroxy-4-(4-hydroxyphenyl)-3,4-dihydrocoumarin. The compounds were tested for estrogenic activity using a yeast-based estrogen screen. Weak estrogenicity was determined for seven members of the series.