6876-65-9

Basic information

• Product Name: Benzeneacetamide, N-(4-methylphenyl)-
• CAS NO: 6876-65-9
• Molecular Formula: C15H15NO
• Molecular Weight: 225.29
• Mol File: 6876-65-9.mol
• Article Data: 37

Chemical Properties

• CAS DataBase Reference: Benzeneacetamide, N-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetamide, N-(4-methylphenyl)-(6876-65-9)
• EPA Substance Registry System: Benzeneacetamide, N-(4-methylphenyl)-(6876-65-9)

Safety Data

• Hazardous Substances Data: 6876-65-9(Hazardous Substances Data)

Upstream product

• 103-82-2 phenylacetic acid 
• 106-49-0 p-toluidine 
• 51463-66-2 dimethyl (2-phenylacetyl)phosphonate 
• 6651-36-1 1-(Trimethylsilyloxy)cyclohexene 
• 681455-21-0 N-[1-(benzotriazol-1-yl)-2-phenylethylidene]-4-methylaniline 
• 201230-82-2 carbon monoxide 
• 108-88-3 toluene 
• 260783-80-0 N,N,N--trimethyl--1--phenylmethanaminium trifluoromethanesulfonate 
• 99-99-0 1-methyl-4-nitrobenzene 
• 13939-06-5 molybdenum hexacarbonyl 
• 25083-02-7 1-(2-phenylacetyl)pyrrolidin-2-one 
• 3085-54-9 N-(4-methylphenyl)formamide 
• 103-83-3 N,N'-dimethylbenzylamine 
• 106-43-4 para-chlorotoluene 

Downstream Products

• 90362-96-2 6-methyl-2-(phenylmethyl)-4(3H)-quinazolinone 
• 19711-87-6 2-oxo-2-diphenyl-N-(p-tolyl)acetamide 
• 103-81-1 Benzeneacetamide 
• 1253778-98-1 2-phenyl-N-(4-((N-(phenylsulfonyl)phenylsulfonamido)methyl)phenyl)acetamide 
• 73108-78-8 6-methyl-3-phenylquinolin-2(1H)-one 
• 934495-95-1 2-phenyl-N-p-tolyl-acetimidoyl chloride 
• 681455-21-0 N-[1-(benzotriazol-1-yl)-2-phenylethylidene]-4-methylaniline 

Relevant articles and documents

Metal-free transamidation of benzoylpyrrolidin-2-one and amines under aqueous conditions

N-Acyl lactam amides, such as benzoylpyrrolidin-2-one, benzoylpiperidin-2-one, and benzoylazepan-2-one reacted with amines in the presence of DTBP and TBAI to afford the transamidated products in good yields. The reactions were conducted under aqueous conditions and good functional group tolerance was achieved. Both aliphatic and aromatic primary amines displayed good activity under metal-free conditions. A radical reaction pathway is proposed.

Nickel (II)-Catalyzed efficient aminocarbonylation of unreactive alkanes with formanilides—Exploiting the deformylation behavior of imides

Challenging functionalization of C(sp3)-H has recently attracted much attention of organic chemists. In this paper, we developed a Ni(acac)2-catalyzed activation of unreactive alkanes with formanilides in the presence of carbon monoxide to furnish moderate to excellent yields of amides. This is the first example of aminocarbonylation of inert alkanes using nickel-based catalyst, and formanilides is disclosed to be an interesting amine source owing to the peculiar deformylation nature of imide intermediates.

Copper-Catalyzed Coupling Reaction of (Hetero)Aryl Chlorides and Amides

Cu2O/N,N′-bis(thiophen-2-ylmethyl)oxalamide is established to be an effective catalyst system for Goldberg amidation with inferior reactive (hetero)aryl chlorides, which have not been efficiently documented by Cu-catalysis to date. The reaction is well liberalized toward a variety of functionalized (hetero)aryl chlorides and a wide range of aromatic and aliphatic primary amides in good to excellent yields. Furthermore, the arylation of lactams and oxazolidinones is achieved. The present catalytic system also accomplished an intramolecular cross-coupling product.