688034-91-5

Upstream product

• 64584-92-5 (R)-pent-4-en-2-ol 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 115414-77-2 (5Z,8Z,11Z,14Z)-(R)-19-(tert-Butyl-diphenyl-silanyloxy)-icosa-5,8,11,14-tetraenoic acid methyl ester 
• 115461-39-7 19(R)-hydroxyeicosatetraenoic acid 
• 1206620-84-9 (3S,5R)-5-(tert-butyl-diphenyl-silanyloxy)-hex-1-en-3-ol 
• 1206620-86-1 (3R,5R)-5-(tert-butyl-diphenyl-silanyloxy)-hex-1-en-3-ol 
• 1286241-85-7 ((2S,3S)-3-((R)-2-(tert-butyldiphenylsilanyloxy)propyl)oxiran-2-yl)methanol 
• 1354689-50-1 (5S,7R)-7,10,10-trimethyl-9,9-diphenyl-5-vinyl-2,4,8-trioxa-9-silaundecane 
• 1354689-55-6 (5R,7R)-7,10,10-trimethyl-9,9-diphenyl-5-vinyl-2,4,8-trioxa-9-silaundecane 
• 183310-90-9 (R)-3-(tert-butyl-diphenyl-silanyloxy)-butyraldehyde 
• 303044-40-8 (2E,5R)-5-{[(1,1-dimethylethyl)diphenylsilyl]oxy}hex-2-en-1-ol 
• 303044-41-9 (2R,3R)-3-{(2R)-2-{[(1,1-dimethylethyl)diphenylsilyl]oxy}propyl}oxirane-2-methanol 
• 303044-39-5 ethyl (2E,5R)-5-{[(tert-butyl)(diphenyl)silyl]oxy}hex-2-enoate 
• 1233961-23-3 ((4S,5S)-5-((R)-2-hydroxypropyl)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate 

Relevant academic research and scientific papers

Carbohydrate/DBU Cocatalyzed Alkene Diboration: Mechanistic Insight Provides Enhanced Catalytic Efficiency and Substrate Scope

A mechanistic investigation of the carbohydrate/DBU cocatalyzed enantioselective diboration of alkenes is presented. These studies provide an understanding of the origin of stereoselectivity and also reveal a strategy for enhancing reactivity and broadening the substrate scope.

Nickel-Catalyzed Enantioselective Conjunctive Cross-Coupling of 9-BBN Borates

Catalytic enantioselective conjunctive cross-coupling between 9-BBN borate complexes and aryl electrophiles can be accomplished with Ni salts in the presence of a chiral diamine ligand. The reactions furnish chiral 9-BBN derivatives in an enantioselective fashion and these are converted to chiral alcohols and amines, or engaged in other stereospecific C?C bond forming reactions.

Stereoselective total synthesis of ophiocerin C through two different approaches

Stereoselective total synthesis of ophiocerin C has been accomplished through two different approaches starting separately from acetaldehyde and from (R)-propylene oxide, and Sharpless asymmetric dihydroxylation has been employed as the key step in both a

First total syntheses of (3 R,5 R)-sonnerlactone and (3 r,5 s)-sonnerlactone

First total syntheses of the macrocyclic natural products (3R,5R)-sonnerlactone and (3R,5S)-sonnerlactone, two new metabolites isolated from the endophytic fungus strain Zh6-B1, have been accomplished in eleven steps with 22% overall yield starting from enantiomerically pure (R)-propylene oxide prepared by hydrolytic kinetic resolution. Other key steps are Sharpless epoxidation, reductive elimination of iodo epoxide, and ring-closing-metathesis reaction for the construction of the macrolactone. Georg Thieme Verlag Stuttgart · New York.

A practical, stereospecific route to 18-, 19-, and 20-hydroxyeicosa-5(Z), 8(Z),11(Z),14(Z)-tetraenoic acids (18-, 19-, and 20-HETEs)

Suzuki-Miyaura cross-coupling of cis-vinylbromide 6, obtained in three steps from diol 4, with functionalized boranes provides a practical, stereospecific route to the title CYP P450 eicosanoids.