68857-44-3

Upstream product

• 85515-02-2 O,O',O''-Triacetyl-N-(tert-butyloxycarbonyl)clionamid 
• 97444-12-7 (2S)-3-(6-bromo-1H-indol-3-yl)-2-[(tert-butoxycarbonyl)amino]propanoic acid 
• 97444-11-6 (RS)-N-Acetyl-6-bromtryptophan-ethylester 
• 97444-10-5 3-(6-Brom-3-indolyl)-2-(hydroxyimino)propancarbonsaeure-ethylester 
• 97444-13-8 6-Brom-N^α-(tert-butyloxycarbonyl)-N-<2-(4-nitrophenylseleno)-2-(3,4,5-triacetoxyphenyl)ethyl>tryptophanamid 
• 97444-01-4 6-Brom-N-<2-hydroxy-2-(3,4,5-triacetoxyphenyl)ethyl>-N^α-(tert-butyloxycarbonyl)tryptophanamid 
• 85515-01-1 6-Brom-N^α-(tert-butyloxycarbonyl)-N-<(3,4,5-triacetoxyphenyl)carbonylmethyl>tryptophanamid 
• 97444-00-3 3,4,5-Triacetoxy-α-aminoacetophenon-hydrochlorid 
• 85515-04-4 (S)-6-Brom-N-(tert-butyloxycarbonyl)tryptophan-pentafluorphenylester 
• 97443-99-7 2-Azido-1-(3,4,5-triacetoxyphenyl)ethanon 
• 85515-06-6 N^α-acetyl-6-bromo-D,L-tryptophan 
• 97443-97-5 2-Diazo-1-(3,4,5-triacetoxyphenyl)ethanon 
• 97443-98-6 2-Chlor-1-(3,4,5-triacetoxyphenyl)ethanon 
• 16732-65-3 6-bromo-indole-2-carboxylic acid(Ref_.7.) 

Relevant academic research and scientific papers

TOTAL SYNTHESIS OF TETRAACETYL CLIONAMIDE

Tetraacetyl clionamide, a 6-bromotryptophan derivative from the sponge Cliona celata was synthesized from gallic acid.

Celenamides A and B, Linear Peptide Alkaloids from the Sponge Cliona celata

Two novel linear peptide alkaloids have been isolated as their hexaacetyl derivatives from acetylated methanol extracts of the sponge Cliona celata.The structures of hexaacetylcelenamide A (3) and B (4) were established by spectroscopic analysis and chemical degradation by ozonolysis and acid-catalyzed hydrolysis.The unique amino acid α,β-didehydro-3,4,5-trihydroxyphenylalanine was shown to be a subunit of both 3 and 4.A small-scale isolation employing acetic-d6 anhydride as the acetylating agent indicated that celenamides A (1) and B (2) were the naturally occurring sponge metabolites.