97444-12-7

Usage

Uses

Used in Pharmaceutical Research and Development:
(2S)-3-(6-bromo-1H-indol-3-yl)-2-[(tert-butoxycarbonyl)amino]propanoic acid is used as a building block for the synthesis of new drugs and therapeutic agents. Its unique structure and functional groups contribute to the creation of novel compounds with potential biological activity.
Used in Drug Synthesis:
(2S)-3-(6-bromo-1H-indol-3-yl)-2-[(tert-butoxycarbonyl)amino]propanoic acid is used as a key intermediate in the synthesis of pharmaceutical compounds, providing a versatile platform for the development of new drugs with improved efficacy and safety profiles.
Further investigation and experimentation are needed to fully understand the potential applications of this chemical in various industries.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 52448-17-6 (2S)-2-amino-3-(6-bromo-1H-indol-3-yl)propanoic acid 
• 85515-06-6 N^α-acetyl-6-bromo-D,L-tryptophan 
• 97444-10-5 3-(6-Brom-3-indolyl)-2-(hydroxyimino)propancarbonsaeure-ethylester 
• 16732-65-3 6-bromo-indole-2-carboxylic acid(Ref_.7.) 
• 52415-29-9 6-bromo-1H-indole 
• 97444-11-6 (RS)-N-Acetyl-6-bromtryptophan-ethylester 
• 691-64-5 di-tert-butyl oxalate 

Downstream Products

• 85515-04-4 (S)-6-Brom-N-(tert-butyloxycarbonyl)tryptophan-pentafluorphenylester 
• 68857-44-3 Tetraacetylclionamid 
• 97444-13-8 6-Brom-N^α-(tert-butyloxycarbonyl)-N-<2-(4-nitrophenylseleno)-2-(3,4,5-triacetoxyphenyl)ethyl>tryptophanamid 
• 97444-01-4 6-Brom-N-<2-hydroxy-2-(3,4,5-triacetoxyphenyl)ethyl>-N^α-(tert-butyloxycarbonyl)tryptophanamid 
• 85515-02-2 O,O',O''-Triacetyl-N-(tert-butyloxycarbonyl)clionamid 
• 85515-01-1 6-Brom-N^α-(tert-butyloxycarbonyl)-N-<(3,4,5-triacetoxyphenyl)carbonylmethyl>tryptophanamid 

Relevant academic research and scientific papers

Indole Alkaloids from the Sea Anemone Heteractis aurora and Homarine from Octopus cyanea

The two new indole alkaloids 2-amino-1,5-dihydro-5-(1H-indol-3-ylmethyl)-4H-imidazol-4-one (1), 2-amino-5-[(6-bromo-1H-indol-3-yl)methyl]-3,5-dihydro-3-methyl-4H-imidazol-4-one (2), and auramine (3) have been isolated from the sea anemone Heteractis auror

Total synthesis of (-)-aspergilazine A

The total synthesis of (-)-aspergilazine A, an alkaloid possessing a rare N1′ to C6 bisindole bond, is described. A palladium-catalyzed N-arylation was used to selectively install the N1′-C6 bond in the presence of three other possible arylation sites. The ligand XPhos displayed a unique capability to efficiently carry out the N-arylation while simultaneously suppressing epimerization of the sensitive C9 stereocenters. This total synthesis has confirmed that aspergilazine A is a dimer of brevianamide F.