68872-14-0Relevant academic research and scientific papers
A novel semi-aromatic polyamide TFC reverse osmosis membrane fabricated from a dendritic molecule of trimesoylamidoamine through a two-step amine-immersion mode
Wu, Hao,Chen, Xiao-Lin,Huang, Xiang,Ruan, Hui-Min,Ji, Yan-Li,Liu, Li-Fen,Gao, Cong-Jie
, p. 39127 - 39137 (2017)
In this work, a novel semi-aromatic polyamide RO membrane was fabricated by using a new self-made dendritic molecule trimesoylamidoamine (TMAAM) as a key functional amine monomer that combined 1,3-diamino-2-propanol (DAP) to react with trimesoyl chloride (TMC) through interfacial polymerization technology. By adjusting the TMAAM concentration and amine-immersion mode, this new TMAAM-based semi-aromatic polyamide RO membrane exhibits simultaneously improved water permeability, antifouling and chlorine-tolerant properties. The introduced TMAAM units in polyamide chains can enhance the TMAAM-based membrane's water flux due to its dendritic structure as well as rich hydrophilic groups, and the DAP-TMAAM-TMC membrane prepared via the new two-step amine-immersion mode has 1.9 times more water flux without loss of salt rejection than the pristine DAP-TMC membrane and also shows higher water flux than the hand-cast conventional aromatic polyamide MPD-TMC membrane, respectively. At the same time, the regularly distributed hydroxyl groups and aliphatic amide bonds in TMAAM units contribute to the improved hydrophilicity and chlorine-tolerant property of the resultant DAP-TMAAM-TMC membrane, respectively. It is also demonstrated that the new two-step amine-immersion mode leads to a much smoother surface which endows the resultant DAP-TMAAM-TMC membrane with a favorable antifouling ability. This research provides us with a promising functional amine monomer and a new membrane formation method to fabricate a high performance RO membrane.
Benzene tricarboxamide derivatives with lipid and ethylene glycol chains self-assemble into distinct nanostructures driven by molecular packing
Aljuaid, Nada,Hamley, Ian W.,Ruokolainen, Janne,Seitsonen, Jani,Tully, Mark
supporting information, p. 8360 - 8363 (2021/08/25)
The self-assembly in aqueous solution of benzene-1,3,5-tricarboxamide (BTA) bearing one alkyl chain and two PEG (polyethylene glycol) chains or two alkyl chains and one PEG chain yields completely distinct nanostructures. Two series of derivatives were sy
Amide-functionalized ionic indium-organic frameworks for efficient separation of organic dyes based on diverse adsorption interactions
Liu, Huiyan,Gao, Guimei,Liu, Jie,Bao, Fenlin,Wei, Yuhui,Wang, Haiying
, p. 2576 - 2584 (2019/04/17)
By varying the solvents, two ionic indium-organic frameworks (1 and 2) were achieved. Both MOFs are constructed from the same indium monomer building units and amide-functionalized linker, but they present distinct topologies along with varied channel sizes and shapes. Importantly, the adsorption potential of the two anionic frameworks towards organic dyes with different charges and sizes was thoroughly examined. Both frameworks exhibited highly selective adsorption of the cationic dye methylene blue (MB) based on preferential electronic affinity and the size-exclusion effect. Besides MB, 1 and 2 also exhibited uptake of cationic dyes rhodamine B (RhB) and rhodamine 6G (R6G) but an inert reaction to the cationic dye crystal violet (CV), and thus additional hydrogen-bonding interactions of the amide groups and dyes during adsorption were suggested. The results also revealed that the adsorption capacity and kinetic constant of 1 are greater than those of 2, showing the importance of porosity and pore structure during adsorption. The adsorption capacity of 1 towards MB is as high as 281 mg g?1 and thus it can potentially serve as a column-chromatographic filler for separating dye molecules.
Tubular and lamellar hydrogen-bonding molecular assemblies of isophthalic acid derivatives bearing a -CONHCnH2 n +1 chain
Lv, Chao,Takeda, Takashi,Hoshino, Norihisa,Akutagawa, Tomoyuki
, p. 22250 - 22258 (2018/06/26)
Isophthalic acid derivatives (CnIP), bearing alkylamide chains (-CONHCnH2n+1: n = 6, 10, 14, and 18) at the 5-position that can participate in hydrogen bonding, were prepared and evaluated for their hydrogen-bonding molecular assembl
A highly porous acylamide decorated MOF-505 analogue exhibiting high and selective CO2 gas uptake capability
Zheng, Baishu,Huang, Lu,Cao, Xiyang,Shen, Shaohua,Cao, Haifei,Hang, Cheng,Zeng, Wenjiang,Wang, Zhaoxu
, p. 1874 - 1881 (2018/04/03)
Porous metal-organic frameworks (MOFs) constructed from organic linkers and metal ions/clusters can provide special pore environments for selective CO2 capture. In this work, we designed and synthesized a highly porous acylamide-functionalized
Self-assembly of homochiral porous supramolecular organic frameworks with significant CO2 capture and CO2/N2 selectivity
Zhou, Yue,Liu, Bing,Sun, Xiaodong,Li, Jiantang,Li, Guanghua,Huo, Qisheng,Liu, Yunling
, p. 6653 - 6659 (2018/05/31)
A pair of homochiral porous supramolecular organic frameworks (JLU-SOF1-R and JLU-SOF1-S) has been assembled from brand-new enantiopure blocks via hydrogen bonding and π-π interactions. The frameworks not only maintain crystallinity well until 250 °C but
Homochiral metal-organic frameworks with enantiopure proline units for the catalytic synthesis of -lactams
Xu, Zhong-Xuan,Tan, Yan-Xi,Fu, Hong-Ru,Liu, Juan,Zhang, Jian
, p. 12199 - 12204 (2015/01/09)
Two enantiopure organic ligands integrating flexible proline units and rigid isophthalate units have been rationally designed and employed for the construction of four homochiral porous metal-organic frameworks (MOFs), respectively. One pair of these MOFs
NOVEL BEXAROTENE ANALOGS
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Page/Page column 20-21, (2011/09/19)
The present invention relates to analogs of bexarotene and methods of use thereof.
Modeling, synthesis and biological evaluation of potential Retinoid X Receptor (RXR) selective agonists: Novel analogues of 4-[1-(3,5,5,8,8- pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene)
Wagner, Carl E.,Jurutka, Peter W.,Marshall, Pamela A.,Groy, Thomas L.,Van Der Vaart, Arjan,Ziller, Joseph W.,Furmick, Julie K.,Graeber, Mark E.,Matro, Erik,Miguel, Belinda V.,Tran, Ivy T.,Kwon, Jungeun,Tedeschi, Jamie N.,Moosavi, Shahram,Danishyar, Amina,Philp, Joshua S.,Khamees, Reina O.,Jackson, Jevon N.,Grupe, Darci K.,Badshah, Syed L.,Hart, Justin W.
experimental part, p. 5950 - 5966 (2010/02/28)
This report describes the synthesis of analogues of 4-[1-(3,5,5,8,8- pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (1), commonly known as bexarotene, and their analysis in acting as retinoid X receptor (RXR)-specific agonists. Compound 1 has FDA approval to treat cutaneous T-cell lymphoma (CTCL); however, its use can cause side effects such as hypothyroidism and increased triglyceride concentrations, presumably by disruption of RXR heterodimerization with other nuclear receptors. The novel analogues in the present study have been evaluated forRXR activation in an RXR mammalian-2-hybrid assay as well as an RXRE-mediated transcriptional assay and for their ability to induce apoptosis as well as for their mutagenicity and cytotoxicity. Analysis of 11 novel compounds revealed the discovery of three analogues that best induce RXR-mediated transcriptional activity, stimulate apoptosis, have comparable Ki and EC50 values to 1, and are selective RXR agonists. Our experimental approach suggests that rational drug design can develop new rexinoids with improved biological properties. 2009 American Chemical Society.
Supramolecular materials from benzene-1,3,5-tricarboxamide-based nanorods
Roosma, Jorg,Mes, Tristan,Leclere, Philippe,Palmans, Anja R. A.,Meijer
, p. 1120 - 1121 (2008/10/09)
Telechelic polymers end-capped or copolymerized with the benzene-1,3,5-tricarboxamide (BTA) moiety lead to supramolecular materials. The intrinsic phase segregation of BTA nanorods with an amorphous polymer such as poly(ethylene butylene) results in therm
