689290-86-6Relevant academic research and scientific papers
4-[6-(2-Aminoethyl)naphthalen-2-yl]benzonitriles are potent histamine H3 receptor antagonists with high CNS penetration
Black, Lawrence A.,Nersesian, Diana L.,Sharma, Padam,Ku, Yi-Yin,Bennani, Youssef L.,Marsh, Kennan C.,Miller, Thomas R.,Esbenshade, Timothy A.,Hancock, Arthur A.,Cowart, Marlon
, p. 1443 - 1446 (2007)
4-[6-(2-Tertiaryaminoethyl)naphthalen-2-yl]benzonitriles are conformationally constrained histamine H3 receptor antagonists with high potency and selectivity. The analogs were designed around a naphthalene core, with the goal of enhancing lipop
Bicyclic-substituted amines as histamine-3 receptor ligands
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Page/Page column 31, (2008/06/13)
Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands and methods for using such comp
