68981-86-2 Usage
Description
4,5-Dihydro-4,4-dimethyl-2-(3-pyridyl)oxazole is a heterocyclic organic compound characterized by a five-membered ring containing nitrogen and oxygen atoms, with the molecular formula C11H13NO. It is often utilized as a building block in the synthesis of pharmaceuticals and agrochemicals, serving as a key intermediate for the production of biologically active compounds. Its unique structure and properties render it valuable for the development of molecules with potential therapeutic applications, making it a significant component in medicinal chemistry and drug discovery research.
Uses
Used in Pharmaceutical Industry:
4,5-Dihydro-4,4-dimethyl-2-(3-pyridyl)oxazole is used as a key intermediate for the synthesis of various pharmaceuticals, contributing to the development of biologically active compounds that can be employed for therapeutic purposes.
Used in Agrochemical Industry:
In the agrochemical sector, 4,5-Dihydro-4,4-dimethyl-2-(3-pyridyl)oxazole is utilized as a building block in the creation of agrochemicals, playing a crucial role in the synthesis of compounds that can be used for agricultural applications, such as pest control and crop protection.
Used in Medicinal Chemistry Research:
4,5-DIHYDRO-4,4-DIMETHYL-2-(3-PYRIDYL)OXAZOLE is used as a research tool in medicinal chemistry, aiding scientists in understanding the structure-activity relationships of potential drug candidates and facilitating the design of new therapeutic agents.
Used in Drug Discovery:
4,5-Dihydro-4,4-dimethyl-2-(3-pyridyl)oxazole is employed in drug discovery processes, where its unique structural features are leveraged to create novel molecules with potential applications in treating various diseases and medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 68981-86-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,8,9,8 and 1 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 68981-86:
(7*6)+(6*8)+(5*9)+(4*8)+(3*1)+(2*8)+(1*6)=192
192 % 10 = 2
So 68981-86-2 is a valid CAS Registry Number.
InChI:InChI=1/C10H12N2O/c1-10(2)7-13-9(12-10)8-4-3-5-11-6-8/h3-6H,7H2,1-2H3
68981-86-2Relevant articles and documents
Secondary Phosphine Oxide Preligands for Palladium-Catalyzed C–H (Hetero)Arylations: Efficient Access to Pybox Ligands
Ghorai, Debasish,Müller, Valentin,Keil, Helena,Stalke, Dietmar,Zanoni, Giuseppe,Tkachenko, Boryslav A.,Schreiner, Peter R.,Ackermann, Lutz
supporting information, p. 3137 - 3141 (2017/09/06)
C–H arylations of oxazolines were accomplished with a well-defined palladium catalyst derived from a secondary bisdiamantyl phosphine oxide. The single-component secondary phosphine oxide (SPO)-palladium complex enabled C–H activations with aryl bromides
Direct synthesis of 2-oxazolines from carboxylic acids using 2-chloro-4,6-dimethoxy-1,3,5-triazine under mild conditions
Bandgar,Pandit
, p. 2331 - 2333 (2007/10/03)
2-Acyloxy-4,6-dimethoxy-1,3,5-triazines obtained from carboxylic acids and 2-chloro-4,6-dimethoxy-1,3,5-triazine were subsequently treated with 2-amino-2-methyl-1-propanol to afford the corresponding 2-oxazolines in excellent yield at room temperature.
The direct synthesis of 2-Oxazolines from carboxylic esters using lanthanide chloride as catalyst
Zhou, Peiwen,Blubaum, Jason E.,Burns, Christopher T.,Natale, Nicholas R.
, p. 7019 - 7020 (2007/10/03)
Using catalytic amounts of lanthanide III (Ln = La, Sm) chlorides and amino alkoxides as reagents, an one-pot direct synthesis for 2-oxazolines, in good yield, from carboxylic esters has been developed.
