69038-04-6

Basic information

• Product Name: N-hydroxysuccinimide ester of 4-(tert-butoxycarbonylamino)butyric acid
• Synonyms: N-hydroxysuccinimide ester of 4-(tert-butoxycarbonylamino)butyric acid
• CAS NO: 69038-04-6
• Molecular Weight: 300.312
• Mol File: 69038-04-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-hydroxysuccinimide ester of 4-(tert-butoxycarbonylamino)butyric acid(CAS DataBase Reference)
• NIST Chemistry Reference: N-hydroxysuccinimide ester of 4-(tert-butoxycarbonylamino)butyric acid(69038-04-6)
• EPA Substance Registry System: N-hydroxysuccinimide ester of 4-(tert-butoxycarbonylamino)butyric acid(69038-04-6)

Safety Data

• Hazardous Substances Data: 69038-04-6(Hazardous Substances Data)

Upstream product

• 74124-79-1 di(succinimido) carbonate 
• 58885-58-8 N-tert-butoxycarbonyl-3-aminopropanol 

Downstream Products

• 66376-36-1 4-amino-1-hydroxybutylidenebisphosphonic acid 
• 129280-53-1 N^γ-tert-butoxycarbonylaminobutyryl-L-tryptophyl-L-leucyl-β-benzyl-L-asparaginic acid α-amide 
• 129280-55-3 N^γ-tert-butoxycarbonylbutyryl-β-benzyl-L-asparaginic acid α-amide 

Relevant articles and documents

Decomposition of 1-(ω-aminoalkanoyl)guanidines under alkaline conditions

The decomposition of some NG-(ω-aminoalkanoyl)argininamides, which are key intermediates for the preparation of radiolabeled and fluorescent neuropeptide Y receptor ligands, prompted us to synthesize a small series of simple 1-(ω-aminoalkanoyl)guanidines, and to investigate these model compounds for stability in alkaline buffers. The degradation of acylguanidines was monitored by time resolved UV spectroscopy. The most labile compound, 1-(5-aminopentanoyl)guanidine, decomposed with a half life of 19 s to yield piperidin-2-one (pH 10.4 at 25 °C). In contrast the half life of 1-(6-aminohexanoyl)guanidine is 7.7 h, which is comparable to the hydrolysis of acetylguanidine (t1/2 = 9.6 h) in alkaline solution.