691005-66-0

Basic information

• Product Name: (+/-)-5-bromo-4-[4-(methylsulfonyl)phenyl]-3-phenylfuran-2(5H)-one
• Synonyms: (+/-)-5-bromo-4-[4-(methylsulfonyl)phenyl]-3-phenylfuran-2(5H)-one
• CAS NO: 691005-66-0
• Molecular Weight: 393.258
• Mol File: 691005-66-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (+/-)-5-bromo-4-[4-(methylsulfonyl)phenyl]-3-phenylfuran-2(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-5-bromo-4-[4-(methylsulfonyl)phenyl]-3-phenylfuran-2(5H)-one(691005-66-0)
• EPA Substance Registry System: (+/-)-5-bromo-4-[4-(methylsulfonyl)phenyl]-3-phenylfuran-2(5H)-one(691005-66-0)

Safety Data

• Hazardous Substances Data: 691005-66-0(Hazardous Substances Data)

Upstream product

• 162011-90-7 rofecoxib 

Downstream Products

• 691005-64-8 (+/-)-3-[4-(methylsulfonyl)phenyl]-5-oxo-4-phenyl-2,5-dihydrofuran-2-yl nitrate 
• 691005-65-9 (+/-)-3-({3-[4-(methylsulfonyl)phenyl]-5-oxo-4-phenyl-2,5-dihydrofuran-2-yl}oxy)benzyl nitrate 
• 213763-81-6 2-cyclopropylmethyl-5-(4-methylsulfonyl)phenyl-4-phenyl-2H-pyridazin-3-one 
• 213764-15-9 5-(4-methylsulfonyl)phenyl-4-phenyl-2H-pyridazin-3-one 
• 185147-17-5 5-Hydroxyrofecoxib 

Relevant articles and documents

Pyridazinones as selective cyclooxygenase-2 inhibitors

Pyridazinone was found to be an excellent core template for selective COX-2 inhibitors. Two potent, selective and orally active COX-2 inhibitors, which were highly efficacious in rat paw edema and rat pyresis models, have been obtained.