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4-Bromo-N'-hydroxybenzenecarboximidamide, commonly known as Boc-NH-ONH2, is a chemical compound characterized by the molecular formula C7H7BrN2O2. It is typically found as a white or off-white powder and is primarily utilized in the synthesis of other chemical products. Due to its potential to cause eye, skin, and respiratory irritation, as well as being harmful if ingested, it is classified as a hazardous product. Proper handling, including storage in a dry, cool, and well-ventilated environment, is essential to ensure safety. 4-BROMO-N'-HYDROXYBENZENECARBOXIMIDAMIDE is extensively used in scientific research and industrial manufacturing, where it functions as a vital intermediate reagent in chemical synthesis.

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  • 69113-23-1 Structure
  • Basic information

    1. Product Name: 4-BROMO-N'-HYDROXYBENZENECARBOXIMIDAMIDE
    2. Synonyms: 4-BROMO-N-HYDROXY-BENZAMIDINE;4-BROMO-N'-HYDROXYBENZENECARBOXIMIDAMIDE;4-BROMOBENZAMIDOXIME;4-bromo-N'-hydroxybenzenecarboximidamide (en)
    3. CAS NO:69113-23-1
    4. Molecular Formula: C7H7BrN2O
    5. Molecular Weight: 215.05
    6. EINECS: N/A
    7. Product Categories: pharmacetical
    8. Mol File: 69113-23-1.mol
  • Chemical Properties

    1. Melting Point: 144-145°C
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-BROMO-N'-HYDROXYBENZENECARBOXIMIDAMIDE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-BROMO-N'-HYDROXYBENZENECARBOXIMIDAMIDE(69113-23-1)
    11. EPA Substance Registry System: 4-BROMO-N'-HYDROXYBENZENECARBOXIMIDAMIDE(69113-23-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 69113-23-1(Hazardous Substances Data)

69113-23-1 Usage

Uses

Used in Scientific Research:
4-Bromo-N'-hydroxybenzenecarboximidamide is employed as a research chemical, facilitating the study of various chemical reactions and processes. Its unique properties make it a valuable tool in the exploration of new chemical pathways and the development of novel compounds.
Used in Industrial Manufacturing:
In the industrial sector, 4-Bromo-N'-hydroxybenzenecarboximidamide is used as an intermediate reagent in the synthesis of a wide range of chemical products. Its role in the production process is critical, as it contributes to the formation of the desired end products.
Used in Chemical Synthesis:
4-Bromo-N'-hydroxybenzenecarboximidamide is used as a key component in chemical synthesis, where it serves as an intermediate reagent. Its presence in the reaction mixture is essential for the successful formation of the target compounds, making it a crucial element in the synthesis process.

Check Digit Verification of cas no

The CAS Registry Mumber 69113-23-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,1,1 and 3 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 69113-23:
(7*6)+(6*9)+(5*1)+(4*1)+(3*3)+(2*2)+(1*3)=121
121 % 10 = 1
So 69113-23-1 is a valid CAS Registry Number.

69113-23-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-BROMO-N'-HYDROXYBENZENECARBOXIMIDAMIDE

1.2 Other means of identification

Product number -
Other names 4-BROMOBENZAMIDOXIME

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:69113-23-1 SDS

69113-23-1Relevant articles and documents

Novel O-acylated amidoximes and substituted 1,2,4-oxadiazoles synthesised from (+)-ketopinic acid possessing potent virus-inhibiting activity against phylogenetically distinct influenza A viruses

Chernyshov, Vladimir V.,Yarovaya, Olga I.,Esaulkova, Iana L.,Sinegubova, Ekaterina,Borisevich, Sophia S.,Popadyuk, Irina I.,Zarubaev, Vladimir V.,Salakhutdinov, Nariman F.

, (2021/12/16)

This article describes the synthesis and antiviral activity evaluation of new substituted 1,2,4-oxadiazoles containing a bicyclic substituent at position 5 of the heterocycle and O-acylated amidoximes as precursors for their synthesis. New compounds were

Catalyst-free, one-pot strategy to access 3-substituted-5-amino-1,2,4-thiadiazoles in water

Nagaraju, Chaithra,Ashok, Swarup Hassan,Narayana, Yatheesh,Nagarakere, Sandhya C.,Kempegowda, Mantelingu,Kanchugarkoppal, Rangappa S.

, p. 3610 - 3619 (2021/10/14)

A protocol has been devised for the synthesis of 3-substituted 5-amino-1,2,4-thiadiazoles utilizing isothiocyanates, amidoximes and water as an eco-friendly solvent. The strategy involves consecutive C?N and S?N bonds formation in a one-pot reaction under

Cobalt-Catalyzed, Directed Intermolecular C-H Bond Functionalization for Multiheteroatom Heterocycle Synthesis: The Case of Benzotriazine

Wu, Weiping,Fan, Shuaixin,Li, Tielei,Fang, Lili,Chu, Benfa,Zhu, Jin

supporting information, p. 5652 - 5657 (2021/08/01)

Transition-metal-catalyzed, directed intermolecular C-H bond functionalization is synthetically useful but heavily underexplored in multiheteroatom heterocycle synthesis. Herein we report a cobalt catalytic method for the formation of a three-nitrogen-bearing benzotriazine scaffold via the coupling of arylhydrazine and oxadiazolone. This synthetic protocol features a low-cost base metal catalyst, a maximum number of heteroatoms built into a heterocycle, a distinct synthetic logic for benzotriazines, a superior step economy, and a broad substrate scope.

Entry into (E)-3-(1,2,4-oxadiazol-5-yl)acrylic acids via a one-pot ring-opening/ring-closing/retro-Diels-Alder reaction sequence

Presnukhina, Sofia,Tarasenko, Marina,Baykov, Sergey,Smirnov, Sergey N.,Boyarskiy, Vadim P.,Shetnev, Anton,Korsakov, Mikhail K.

supporting information, (2019/12/27)

A simple and convenient one-pot method is reported for the synthesis of (E)-3-(3-aryl(heteroaryl, alkyl)-1,2,4-oxadiazole-5-yl)acrylic acids utilizing readily accessible or commercially available substituted benzamidoximes and inexpensive exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride. The method is based on the reaction of amidoximes with the anhydride in a basic medium at RT followed by an acid-catalyzed retro-Diels-Alder reaction. The observed stereoselective heterocyclization/retro-Diels-Alder cascade process is suitable for the synthesis of a wide range of substituted (E)-1,2,4-oxadiazole-5-ylacrylic acids featuring electron donating and electron withdrawing groups on the aryl moiety, as well as heteroaryl or alkyl substituents at position 3 of the 1,2,4-oxadiazole ring (42–79%; 15 examples).

Synthesis and Evaluation of Antibacterial Activity of 1,2,4-Oxadiazole-Containing Biphenylcarboxylic Acids

Baikov, S. V.,Presnukhina, S. I.,Shetnev, A. A.,Tarasenko, M. V.

, p. 1611 - 1619 (2020/10/15)

Abstract: A one-pot method for the synthesis of biphenylcarboxylic acids containing 1,2,4-oxadiazole ring in the NaOH–DMSO system was developed. The results of in vitro experiments showed that the synthesized compounds exhibit antibacterial activity against susceptible strains of E. coli and S. aureus.

1,2,4-Oxadiazole ring–containing pyridylpyrazole-4-carboxamides: Synthesis and evaluation as novel insecticides of the anthranilic diamide family

Khallaf, Abdalla,Liu, Hui,Wang, Ping,Zhu, Hongjun,Zhuo, Shuping

supporting information, (2020/02/18)

Herein, we describe the preparation of pyridylpyrazole-4-carboxamides containing a 1,2,4-oxadiazole ring as novel anthranilic diamide derivatives and compare their insecticidal activities to that of chlorantraniliprole, a well-established potent insectici

Discovery of 1,2,4-oxadiazole derivatives as a novel class of noncompetitive inhibitors of 3-hydroxykynurenine transaminase (HKT) from Aedes aegypti

Guido, Rafael V. C.,Leal, Laylla L. L.,Maciel, Larissa G.,Oliveira, Andrew A.,Rom?o, Tatiany P.,Silva-Filha, Maria Helena N. L.,Soares, Thereza A.,dos Anjos, Janaína V.

, (2020/01/03)

The mosquito Aedes aegypti is the vector of arboviruses such as Zika, Chikungunya, dengue and yellow fever. These infectious diseases have a major impact on public health. The unavailability of effective vaccines or drugs to prevent or treat most of these

SO2F2-Mediated one-pot cascade process for transformation of aldehydes (RCHO) to cyanamides (RNHCN)

Ding, Chengrong,Ge, Shuting,Wei, Junjie,Zhang, Guofu,Zhao, Yiyong

, p. 17288 - 17292 (2020/05/18)

A simple, mild and practical cascade process for the direct conversion of aldehydes to cyanamides was developed featuring a wide substrate scope and great functional group tolerability. This method allows for transformations of readily available, inexpensive, and abundant aldehydes to highly valuable cyanamides in a pot, atom, and step-economical manner with a green nitrogen source. This protocol will serve as a robust tool for the installation of the cyanamide moiety in various complicated molecules.

Synthesis of Some Azamacrocycles Bearing 1,2,4-Oxadiazole and 1,2,3-Triazole Moieties

?zer, B.,Dürüst, Y.

, p. 698 - 705 (2020/06/01)

Abstract: A tetraazacrown ether,4,9-di(prop-2-yn-1-yl)-1,4,9,12-tetraazacyclohexadecane-2,11-dione, bearingpropargyl groups on two nitrogens was synthesized starting from1,4,9,12-tetraazacyclohexadecane-2,11-dione and subjected to 1,3-cycloadditionreactio

Synthesis and Anticancer Activity of Novel Actinonin Derivatives as HsPDF Inhibitors

Hu, Liu,Cai, Xing,Dong, Suzhen,Zhen, Yongjia,Hu, Jidi,Wang, Shenjun,Jiang, Jingwen,Huang, Jiawu,Han, Yuqiao,Qian, Yu,Yuan, Yanqiu,Hu, Wenhao

, p. 6959 - 6978 (2020/08/14)

Human mitochondrial peptide deformylase (HsPDF) is responsible for removing the formyl group from N-terminal formylmethionines of newly synthesized mitochondrial proteins and plays important roles in maintaining mitochondria function. It is overexpressed

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