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2',5-difluoro-2'-deoxy-1-arabinosyluracil, also known as gemcitabine, is a nucleoside analog and chemotherapy drug that is used to treat various forms of cancer. It works by inhibiting the growth of cancer cells and preventing the replication of their DNA.

69123-95-1

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69123-95-1 Usage

Uses

Used in Oncology:
2',5-difluoro-2'-deoxy-1-arabinosyluracil is used as an anticancer agent for the treatment of various forms of cancer, including breast, lung, pancreatic, and bladder cancer. It is effective in both first-line and adjuvant treatment of certain cancers and is often used in combination with other chemotherapy drugs.
Used in Drug Administration:
2',5-difluoro-2'-deoxy-1-arabinosyluracil is administered intravenously and is converted into its active form within the body. It has been found to be well-tolerated in many patients, with common side effects including nausea, vomiting, and low blood cell counts.

Check Digit Verification of cas no

The CAS Registry Mumber 69123-95-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,1,2 and 3 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 69123-95:
(7*6)+(6*9)+(5*1)+(4*2)+(3*3)+(2*9)+(1*5)=141
141 % 10 = 1
So 69123-95-1 is a valid CAS Registry Number.
InChI:InChI=1/C9H10F2N2O5/c10-3-1-13(9(17)12-7(3)16)8-5(11)6(15)4(2-14)18-8/h1,4-6,8,14-15H,2H2,(H,12,16,17)/t4-,5+,6-,8-/m0/s1

69123-95-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-ethylhexanoic acid,methane

1.2 Other means of identification

Product number -
Other names 2',5-difluoro-2'-deoxy-1-arabinosyluracil

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:69123-95-1 SDS

69123-95-1Upstream product

69123-95-1Downstream Products

69123-95-1Relevant academic research and scientific papers

A general synthesis of 2′-deoxy-2′-[18F]fluoro-1-β-D- arabinofuranosyluracil and its 5-substituted nucleosides

Alauddin, Mian M.,Conti, Peter S.,Fissekis, John D.

, p. 285 - 289 (2007/10/03)

Several 2′-deoxy-2′-[18F]fluoro-1-β-D- arabinofuranosyluracil derivatives have been synthesized. Coupling of 1-bromo-2-deoxy-2-[18F]fluoro-3,5-di-O-benzoyl-α-D- arabinofuranose 2 with protected uracil derivatives 3a-e followed by hydrolysis and high-performance liquid chromatography purification produced the radiolabeled nucleosides 4a-e in 15-30% yield (d. c.), > 99% radiochemical purity and 55.5-103.6 GBq/μmol specific activities. Copyright

Anti-herpes virus compositions containing 5-substituted 1-2'(deoxy-2-'-substituted-β-d-arabinofuranosyl)pyrimedene nucleosides

-

, (2008/06/13)

Veterinarian composition for the treatment of herpes virus in animals comprising a pyrimidine nucleoside, or veterinarianically acceptable acid addition salte thereof, of the formula STR1 wherein A is OR3, SR3, NR3 R4

5-Substituted 1-(2'-Deoxy-2'-substituted-β-D-arabinofuranosyl)pyrimidine nucleosides

-

, (2008/06/13)

Pyrimidine nucleosides exhibiting anti-viral and anti-tumor effects have the formula STR1 wherein A is OR3, SR3, NR3 R4 or NHacyl wherein R3 and R4 are the same or different and are hydroge

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