69159-49-5

Usage

Uses

Used in Pharmaceutical Industry:
1-Benzhydryl-N-methyl-3-azetidinamine is used as an antihistamine medication for the treatment of allergic conditions such as hay fever, hives, and allergic skin rashes. It is valued for its effectiveness in blocking histamine action, leading to relief from allergy symptoms.
Used in Allergy Management:
Desloratadine is utilized as a therapeutic agent for managing allergic responses, providing a longer-lasting solution compared to its parent compound, loratadine. Its higher efficacy and favorable tolerability profile contribute to its widespread use in allergy management.
Used in Non-Sedative Allergy Treatment:
1-Benzhydryl-N-methyl-3-azetidinamine is used as a non-sedating antihistamine, making it suitable for individuals who require allergy relief without the side effect of drowsiness. This attribute is particularly beneficial for those who need to remain alert during the day while treating their allergic symptoms.

InChI:InChI=1/C17H20N2/c1-18-16-12-19(13-16)17(14-8-4-2-5-9-14)15-10-6-3-7-11-15/h2-11,16-18H,12-13H2,1H3

Upstream product

• 33301-41-6 1-benzhydryl-3-azetidinyl methanesulfonate 
• 74-89-5 methylamine 
• 18621-17-5 1-(diphenylmethyl)-3-hydroxyazetidine 

Downstream Products

• 854038-91-8 N-(1-benzhydrylazetidin-3-yl)-N-methylcarbamic acid tert-butyl ester 
• 935668-13-6 N-(1-benzhydryl-3-azetidino)-N-methylacetamide 
• 147293-68-3 1-(diphenylmethyl)-3-azetidine 
• 133891-77-7 3-(methylamino)azetidine dihydrochloride 

Relevant academic research and scientific papers

Macrocyclic Spiro Pyrimidine Derivatives

Macrocyclic spiro pyrimidine compounds, compositions comprising such compounds, methods for making the compounds, and methods of treating and preventing the progression of diseases, conditions, and disorders using such compounds and compositions are described herein.

MACROCYCLIC BENZOFUSED PYRIMIDINE DERIVATIVES

Macrocyclic benzofused pyrimidine compounds, compositions comprising such compounds, methods for making the compounds, and methods of treating and preventing the progression of diseases, conditions and disorders using such compounds and compositions are described herein.

AMINO PYRIMIDINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS

The present invention relates to novel amino pyrimidine compounds of formula (I) for the modulation of the histamine H4 receptor and the treatment or prevention of conditions mediated by the histamine H4 receptor. The invention also relates to the preparation of such compounds.

1,8 benzonaphthyridine derivatives and antimicrobial compositions

This invention relates to a novel 1,8 benzo[b]naphythyridine derivative of general formula (I), STR1 wherein R is H or a hydroxy, amino or alkylamino radical optionally substituted by amino or hydroxy, or R is dialkylamino of which the alkyl portions may

7-Azetidinylquinolones as antibacterial agents. Synthesis and structure- activity relationships

A series of novel antibacterial quinolones and naphthyridones has been prepared which contain 7-azetidinyl substituents in place of the usual piperazine or aminopyrrolidine groups. These azetidinyl derivatives were evaluated for in vitro activity by deter

Quantitative structure-activity relationships of antibacterial agents, 7-heterocyclic amine substituted 1-cyclopropyl-6,8-difluoro-4-oxoquinoline-3-carboxylic acids

Quantitative structure-activity relationships (QSAR) of various 7-(3-substituted-azetidin-1-yl)-1-cyclopropyl-6,8-difluoro-1,4-dihydro -4-oxoquinoline-3-carboxylic acids, 14-25, were studied to clarify the structural requirements for 3-substituted azetidi