69172-21-0

Upstream product

• 1166181-77-6 methyl 4-[4-(benzyloxy)phenyl]butanoate 
• 243641-03-4 C₁₈H₁₈O₃ 
• 836-42-0 4-benzyloxybenzyl chloride 
• 4521-28-2 4-(4-Methoxyphenyl)butyric acid 
• 7021-11-6 4-(4-hydroxyphenyl)butanoic acid 
• 6686-26-6 4-(4-benzyloxyphenyl)butyric acid 

Downstream Products

• 75676-93-6 7-(p-benzyloxyphenyl)-trans-3-hepten-2-one 
• 6952-35-8 6-(4-hydroxyphenyl)hexanoic acid 
• 113379-10-5 methyl 6-(4-hydroxyphenyl)hexanoate 
• 944335-22-2 (2S)-4-[4-(benzyloxy)phenyl]butane-1,2-diol 
• 944335-23-3 (2S)-4-[4-(benzyloxy)phenyl]-2-hydroxybutyl 4-methyl-1-benzenesulfonate 
• 1010127-34-0 (2S)-2-{2-[4-(benzyloxy)phenyl]ethyl}oxirane 
• 767330-04-1 (-)-(3S)-1-[4-(benzyloxy)phenyl]hex-5-en-3-ol 
• 1638640-04-6 ({(3S)-1-[4-(benzyloxy)phenyl]hex-5-en-3-yl}oxy)(tert-butyl)(dimethyl)silane 
• 1638640-11-5 C₂₅H₃₆O₃Si 
• 1258516-47-0 {(1S)-3-[4-(benzyloxy)phenyl]-1-{[(2S)-oxiran-2-yl]methyl}propoxy}(tert-butyl)dimethylsilane 
• 1443256-45-8 (3S,5R)-1-(4-hydroxyphenyl)nonadecane-3,5-diol 
• 1638640-10-4 C₂₃H₂₅NO₃ 
• 69172-19-6 5H-r,8-(p-benzyloxyphenyl)-cis-4-bromo-cis-3-hydroxy-trans-3-methyloctan-5-olide 

Relevant academic research and scientific papers

An efficient process for the synthesis of γ-arylbutanals via copper-mediated Grignard coupling

Copper-mediated Grignard cross-coupling of β-bromoethylene acetals with substituted benzyl halides can be combined with hydrolytic deprotection for an efficient and practical scale-up process to form γ-arylbutanals.

Stereoselective total synthesis of phenolic nonadecanediol

A simple and highly efficient synthetic route has been developed for synthesis of 1-(4-hydroxyphenyl)nonadecane-3,5-diol (1). The two stereogenic centers were generated by employing proline asymmetric α-hydroxylation (MacMillan α-hydroxylation), Jacobsen's hydrolytic kinetic resolution (HKR), and, finally, Yamaguchi oxirane opening as key steps (Scheme 2). Copyright

Initial structure-activity relationship of a novel class of nonpeptidyl GnRH receptor antagonists: 2-arylindoles

A nonpeptidyl GnRH receptor antagonist (1), with a unique 2-arylindole core, was identified through the Merck in-house screening for binding affinity on the rat GnRH receptor. SAR studies directed toward the alkoxy-ethanolamine and 2-aryl groups resulted in a simpler lead structure with improved activity. This compound 50 exhibits a 60-fold improvement in binding activity over our initial lead 1.

1-(3,4-dihydroxyphenyl)-2-(4-(4-hydroxyphenyl)butaylamino)ethanol

Methods and devices for the diagnosis, evaluation and treatment of coronary artery disease (CAD) by means of a closed-loop drug delivery system that delivers an exercise simulating agent, including novel exercise simulating agents which elicit both acute