69262-89-1Relevant academic research and scientific papers
HIGHLY STEREOSELECTIVE REDUCTION OF α-METHYLTHIO AND α-PHENYLTHIO KETONES---SYNTHESIS OF syn- AND anti-β-METHYLTHIO- AND β-PHENYLTHIOALCOHOLS---
Shimagaki, Masayuki,Maeda, Tadashi,Matsuzaki, Yuji,Hori, Ishaburo,Nakata, Tadashi,Oishi, Takeshi
, p. 4775 - 4778 (2007/10/02)
Reduction of α-methylthio and α-phenylthio ketones 1 with L- selectride gave syn-alcohols 2 in high stereoselectivity except when R1 was cyclohexyl group, while reduction with Zn(BH4)2 gave the isomeric anti-alcohols 3 provided R3 was a methyl group.
ACYCLIC STEREOCONTROL IN THE ADDITION OF γ-ALKYLTHIO-ALLYLBORONATES TO ALDEHYDES
Hoffmann, Reinhard W.,Kemper, Bruno
, p. 2219 - 2224 (2007/10/02)
The Z-isomer 10 of the γ-alkylthio-allylboronates adds to aldehydes giving the syn diastereomer 4 of the product homoallyl-alcohol.The E-isomer 12 leads in turn to the anti-diastereomer 5 with a high degree of acyclic stereocontrol.Kinetic diasteroselecti
