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692771-01-0

5-(2-fluorophenyl)-3-(3-methylphenyl)-1,2,4-oxadiazole is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 692771-01-0 Structure

  • Basic information

    1. Product Name: 5-(2-fluorophenyl)-3-(3-methylphenyl)-1,2,4-oxadiazole
    2. Synonyms: 5-(2-fluorophenyl)-3-(3-methylphenyl)-1,2,4-oxadiazole
    3. CAS NO:692771-01-0
    4. Molecular Formula:
    5. Molecular Weight: 254.264
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 692771-01-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 401.3±55.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: 1.212±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 5-(2-fluorophenyl)-3-(3-methylphenyl)-1,2,4-oxadiazole(CAS DataBase Reference)
    10. NIST Chemistry Reference: 5-(2-fluorophenyl)-3-(3-methylphenyl)-1,2,4-oxadiazole(692771-01-0)
    11. EPA Substance Registry System: 5-(2-fluorophenyl)-3-(3-methylphenyl)-1,2,4-oxadiazole(692771-01-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 692771-01-0(Hazardous Substances Data)

692771-01-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 692771-01-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,9,2,7,7 and 1 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 692771-01:
(8*6)+(7*9)+(6*2)+(5*7)+(4*7)+(3*1)+(2*0)+(1*1)=190
190 % 10 = 0
So 692771-01-0 is a valid CAS Registry Number.

692771-01-0Downstream Products

692771-01-0Relevant articles and documents

Enhancement of premature stop codon readthrough in the CFTR gene by Ataluren (PTC124) derivatives

Pibiri, Ivana,Lentini, Laura,Melfi, Raffaella,Gallucci, Giulia,Pace, Andrea,Spinello, Angelo,Barone, Giampaolo,Di Leonardo, Aldo

, p. 236 - 244 (2015)

Abstract Premature stop codons are the result of nonsense mutations occurring within the coding sequence of a gene. These mutations lead to the synthesis of a truncated protein and are responsible for several genetic diseases. A potential pharmacological

Electrochemical synthesis of 1,2,4-oxadiazoles from amidoximes through dehydrogenative cyclization

Hu, Aixi,Jiang, chan,Li, mingfang,Xu, Leitao,Ye, Jiao,Yi, Yangjie

, p. 10611 - 10616 (2021/12/27)

A convenient and efficient method for the generation of the iminoxy radical through anodic oxidation was developed for the synthesis of 3,5-disubstituted 1,2,4-oxadiazoles fromN-benzyl amidoximes. The transformation proceeds through 1.5-Hydrogen Atom Transfer (1,5-HAT) and intramolecular cyclization. The process features simple operation, mild conditions, broad substrate scope and high functional group compatibility, and provides a facile and practical way for the preparation of 1,2,4-oxadiazoles.

NBS-mediated practical cyclization of N-acyl amidines to 1,2,4-oxadiazoles via oxidative N?O bond formation

Li, Ertong,Wang, Manman,Wang, Zhen,Yu, Wenquan,Chang, Junbiao

, p. 4613 - 4618 (2018/07/31)

A reaction involving an efficient NBS-mediated oxidative N?O bond formation has been established for the synthesis of 1,2,4-oxadiazoles from readily accessible N-acyl amidines. The features of this synthetic method include simplicity of operation, mild re

Copper-catalyzed direct synthesis of 1,2,4-oxadiazoles from amides and organic nitriles by oxidative N-O bond formation

Kuram, Malleswara Rao,Kim, Woo Gyum,Myung, Kyungjae,Hong, Sung You

supporting information, p. 438 - 442 (2016/02/19)

Herein, we report the first Cu-catalyzed one-step method for the synthesis of 1,2,4-oxadiazoles from stable, less toxic, and readily available amides and organic nitriles by a rare oxidative N-O bond formation using O2 as sole oxidant. This met

A convenient and mild method for 1,2,4-oxadiazole preparation: Cyclodehydration of O-acylamidoximes in the superbase system MOH/DMSO

Baykov, Sergey,Sharonova, Tatyana,Osipyan, Angelina,Rozhkov, Sergey,Shetnev, Anton,Smirnov, Alexey

supporting information, p. 2898 - 2900 (2016/06/14)

Herein, we reported a general, convenient, and efficient synthesis of 3,5-disubstituted-1,2,4-oxadiazoles via cyclodehydration of O-acylamidoximes in the superbase system MOH/DMSO (M = Li, Na, K). Excellent isolated yields (up to 98%) were attained within

A metal-free tandem approach to prepare structurally diverse N-heterocycles: Synthesis of 1,2,4-oxadiazoles and pyrimidinones

Gupta, Puneet K.,Hussain, Mohd. Kamil,Asad, Mohd.,Kant, Ruchir,Mahar, Rohit,Shukla, Sanjeev K.,Hajela, Kanchan

, p. 3062 - 3070 (2014/07/07)

A metal-free one-pot approach to the diversity oriented synthesis of N-heterocycles, 1,2,4-oxadiazoles and 2,6 disubstituted pyrimidin-4-ones is described via carboxamidation of amidines with aryl carboxylic acids and aryl propargylic acids. The reactions occur at room temperature forming N-acylamidines which undergo tandem nucleophilic addition-deamination- intramolecular cyclisation to give the corresponding heterocyclic compounds in good to excellent yields. This one pot approach has led to the successful synthesis of the drug lead molecule, ataluren, 3-(5-(2-fluorophenyl)-1,2,4- oxadiazol-3-yl) benzoic acid in two steps. the Partner Organisations 2014.

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