20680-59-5 Usage
Uses
Used in Pharmaceutical Research and Development:
3-Methylbenzenecarboximidamide hydrochloride is used as a potential antineoplastic agent in pharmaceutical research and development. It is being studied for its potential anti-cancer properties, making it a promising candidate for the development of new cancer treatments.
Used in Organic Synthesis:
In the field of organic synthesis, 3-Methylbenzenecarboximidamide hydrochloride serves as a building block for the preparation of various organic compounds. Its unique structure and properties make it a valuable component in the synthesis of a wide range of organic molecules, contributing to the advancement of chemical research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 20680-59-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,6,8 and 0 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 20680-59:
(7*2)+(6*0)+(5*6)+(4*8)+(3*0)+(2*5)+(1*9)=95
95 % 10 = 5
So 20680-59-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H10N2.ClH/c1-6-3-2-4-7(5-6)8(9)10;/h2-5H,1H3,(H3,9,10);1H
20680-59-5Relevant academic research and scientific papers
Preparation of Triazolopyrimidines as Potential Antiasthma Agents
Medwid, Jeffrey B.,Paul, Rolf,Baker, Jannie S.,Brockman, John A.,Du, Mila T.,et al.
, p. 1230 - 1241 (2007/10/02)
With the use of the human basophil histamine release assay, 5-aryl-2-aminotriazolopyrimidines were found to be active as mediator release inhibitors.These compounds were prepared by reacting arylamidines with sodium ethyl formylacetate or with ethyl propiolate to give pyrimidinones.Treatment with phosphorus oxychloride gave a chloropyrimidine, which was converted to a hydrazinopyrimidine with hydrazine.Cyclization, using cyanogen bromide, gave the triazolopyrimidines, after a Dimroth rearrangement.Following a structure-activity evaluation, the5--2-amino (8-10), 5-(3-bromophenyl)-2-amino (8-13), 5--2-amino (8-11), and 5-(4-pyridinyl)-2-amino (6-7) compounds were found to have the best activity.They were chosen for further pharmacological and toxicological study.
