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L-ARGININE 7-AMIDO-4-METHYLCOUMARIN DIHYDROCHLORIDE is a fluorogenic peptide-based substrate that is commonly used in the study and monitoring of various enzymes and their activities.
Used in Enzyme Activity Monitoring:
L-ARGININE 7-AMIDO-4-METHYLCOUMARIN DIHYDROCHLORIDE is used as a substrate for monitoring the activity of enzymes such as cathepsin H from rat muscle homogenate and sarcoplasmic extract, arginine amino-peptidase from Daphnia homogenates, and recombinant aminopeptidase from Toxoplasma gondii. It serves as a valuable tool in understanding the function and regulation of these enzymes.
Used in Thrombin Activity Monitoring:
L-ARGININE 7-AMIDO-4-METHYLCOUMARIN DIHYDROCHLORIDE is used as a substrate for monitoring thrombin activity, which is crucial in the study of blood clotting and related medical conditions. Its use in this context helps researchers to better understand the mechanisms of thrombin and its role in hemostasis and thrombosis.

69304-16-1

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69304-16-1 Usage

Biochem/physiol Actions

L-Arginine-7-amido-4-methylcoumarin hydrochloride is a protease substrate. It is a specific substrate for cathepsin H and not for cathepsin L and B.

Check Digit Verification of cas no

The CAS Registry Mumber 69304-16-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,3,0 and 4 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 69304-16:
(7*6)+(6*9)+(5*3)+(4*0)+(3*4)+(2*1)+(1*6)=131
131 % 10 = 1
So 69304-16-1 is a valid CAS Registry Number.
InChI:InChI=1/C16H21N5O3.ClH/c1-9-7-14(22)24-13-8-10(4-5-11(9)13)21-15(23)12(17)3-2-6-20-16(18)19;/h4-5,7-8,12H,2-3,6,17H2,1H3,(H,21,23)(H4,18,19,20);1H/t12-;/m0./s1

69304-16-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S)-2-amino-5-(diaminomethylideneamino)-N-(4-methyl-2-oxochromen-7-yl)pentanamide,hydrochloride

1.2 Other means of identification

Product number -
Other names L-Arginine-7-amido-4-methylcoumarin hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:69304-16-1 SDS

69304-16-1Relevant academic research and scientific papers

A macrocyclic coumarin-containing tripeptide via CuAAC chemistry

Van Berkel, Sander S.,Van Der Lee, Bas,Van Delft, Floris L.,Rutjes, Floris P. J. T.

supporting information; experimental part, p. 4272 - 4274 (2011/03/19)

A Cu-catalysed macrocyclisation was performed to obtain a macrocyclic coumarin-containing tripeptide for use in thrombin activity measurements.

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