69321-55-7

Basic information

• Product Name: Benzenethiol, 5-bromo-2-methyl-
• CAS NO: 69321-55-7
• Molecular Formula: C7H7BrS
• Molecular Weight: 203.103
• Mol File: 69321-55-7.mol

Chemical Properties

• CAS DataBase Reference: Benzenethiol, 5-bromo-2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenethiol, 5-bromo-2-methyl-(69321-55-7)
• EPA Substance Registry System: Benzenethiol, 5-bromo-2-methyl-(69321-55-7)

Safety Data

• Hazardous Substances Data: 69321-55-7(Hazardous Substances Data)

Upstream product

• 39478-78-9 5-bromo-2-methylaniline 
• 1093847-06-3 S-5-bromo-2-methylphenyl O-ethylcarbonodithioate 
• 60956-26-5 4-bromo-2-nitrotoluene 

Downstream Products

• 101084-00-8 5-Brom-2-methyl-phenylsulfenylchlorid 
• 845746-13-6 (5-bromo-2-methyl-phenylsulfanyl)-acetic acid tert-butyl ester 
• 142994-01-2 4-bromo-2-(methylsulphenyl)toluene 
• 1859141-26-6 1-((2-((2-((7-chloroquinolin-4-yl)amino)ethyl)(methyl)amino)ethyl)amino)-4-methyl-9H-thioxanthen-9-one 

Relevant articles and documents

ISOXAZOLINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS

Disclosed are Compounds of Formula (1) or (1'), wherein Q is (Q-1) or (Q-2); and R1, R2, R3, J and X are as defined in the disclosure. Also disclosed are compositions containing the Compounds of Formula (1) or Formula (1') and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a Compound or a composition of the invention.

Subtle "supramolecular buttressing effects" in Cucurbit[7]uril/guest assemblies

Biphenyl derivatives bearing a dimethylsulfonium group at position 3 and three different substituents at position 4 (H, F and CH3) have been prepared as probes to test the validity of the "supramolecular buttressing" concept. We define the latter as the alteration, by a neighboring unit, of a substituent effect on intermolecular recognition. In this case, the 4-substituents exert some pressure on the 3-dimethylsulfonium groups and control the ratio of their syn and anti conformations. As free species, biphenyls bearing 4-H and 4-F substituents are present as approximately equimolar mixtures of syn and anti-conformers, while the biphenyl scaffold with a 4-CH3 group adopts the anti-conformation exclusively. The 3-dimethylsulfonium substituents then interact with one of the carbonylated portals of Cucurbit[7]uril (CB[7]), and their conformations affect the position of the guests inside the cavity of the macrocycle, thereby validating our "supramolecular buttressing" model. Surprisingly however, binding affinities towards CB[7] are barely affected by the nature of the 4-substituents and the conformations of the neighboring sulfonium groups, despite very different electronic densities presented to the CB[7] portal in their syn or anti conformations. Solvation was found to dramatically smoothen host-guest Columbic interactions, although the latter remain important in the recognition process. Replacing the positively charged 3-dimethylsulfonium unit with an isopropyl substituent decreases the affinity of the biphenyl guest by 1000-fold. The Royal Society of Chemistry 2013.

PYRANOBENZOTHIOPHENE DERIVATIVES TO TREAT INFECTION WITH HEPATITIS C VIRUS

The invention is directed to a compound of the formula: (I) wherein substitutions at R1, R2 , R3 - R12,and Y are set forth in the specification; pharmaceutical compositions comprising said compound, methods of treating or preventing a Hepatitis C viral infection in a mammal comprising contacting the mammal with an effective amount of said compound or pharmaceutical compositions including said compound and methods of inhibiting replication of a Hepatitis C virus comprising contacting the HCV virus with an effective amount of said compound or pharmaceutical compositions including said compound.