69333-51-3Relevant academic research and scientific papers
Dimeric Potassium Amide-Catalyzed α-Alkylation of Benzyl Sulfides and 1,3-Dithianes
Liu, Yu-Feng,Zheng, Lei,Zhai, Dan-Dan,Zhang, Xiang-Yu,Guan, Bing-Tao
, p. 5351 - 5356 (2019)
The first catalytic α-alkylation reaction of benzyl sulfides and 1,3-dithianes with styrenes and conjugated dienes was developed under mild conditions by using a readily available Br?nsted base potassium bis(trimethylsilyl)amide (KHMDS) as catalyst. The reaction displayed good functional group tolerance, high efficiency, and excellent chemoselectivity. A series of desired alkylation products were obtained in good to high yield. Preliminary mechanism studies suggested that two of the potassium amide catalyst molecules worked together in the catalytic cycle.
Gold-catalyzed C-S bond formation from thiols
Jean, Micka?l,Renault, Jacques,van de Weghe, Pierre,Asao, Naoki
supporting information; experimental part, p. 378 - 381 (2010/03/24)
ortho-Alkynylbenzoic acid alkyl esters act as alkylating agents of thiol derivatives with PPh3AuCl in combination with AgOTf in 1,2-dichloroethane at 80 °C. The corresponding sulfide compounds are obtained in good to excellent yields.
