69367-52-8

Basic information

• Product Name: Butanoic acid, 2-bromo-3-methyl-, methyl ester, (S)-
• CAS NO: 69367-52-8
• Molecular Formula: C6H11BrO2
• Molecular Weight: 195.056
• Mol File: 69367-52-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Butanoic acid, 2-bromo-3-methyl-, methyl ester, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 2-bromo-3-methyl-, methyl ester, (S)-(69367-52-8)
• EPA Substance Registry System: Butanoic acid, 2-bromo-3-methyl-, methyl ester, (S)-(69367-52-8)

Safety Data

• Hazardous Substances Data: 69367-52-8(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 10323-40-7 2-bromoisovaleric acid 
• 83818-65-9 ((Z)-1-Chloro-3-methyl-but-1-enylsulfanyl)-benzene 
• 503-74-2 3-methylbutyric acid 

Downstream Products

• 924-50-5 Methyl 3,3-dimethylacrylate 
• 22167-31-3 2-(p-Chlorbenzoylaminoxy)-3-methyl-buttersaeuremethylester 
• 14664-79-0 β-Hydroxy-α-isopropylbenzenpropionsaeure-methylester 
• 70304-35-7 2-(Methoxycarbonylamino)isovaleriansaeure-methylester 
• 112344-91-9 cis-3-isopropyl-1-(4-methoxyphenyl)-4-styrylazetidin-2-one 
• 112344-92-0 (3R*,4R*)-3-isopropyl-1-(4-methoxyphenyl)-4-((E)-styryl)azetidin-2-one 
• 123121-16-4 (3S,4S)-3-Isopropyl-4-((E)-1-methyl-2-phenyl-vinyl)-1-((S)-1-phenyl-ethyl)-azetidin-2-one 
• 123003-93-0 (3R,4S)-3-Isopropyl-4-((E)-1-methyl-2-phenyl-vinyl)-1-((R)-1-phenyl-ethyl)-azetidin-2-one 
• 123050-68-0 (3R,4S)-3-Isopropyl-4-((E)-1-methyl-2-phenyl-vinyl)-1-((S)-1-phenyl-ethyl)-azetidin-2-one 
• 123164-75-0 cis-3-isopropyl-4-(α-methylstyryl)-1-(4-methoxyphenyl)azetidin-2-one 
• 122598-57-6 trans-3-isopropyl-4-(α-methylstyryl)-1-(4-methoxyphenyl)azetidin-2-one 
• 616-45-5 2-pyrrolidinon 
• 2857-97-8 trimethylsilyl bromide 
• 150312-71-3 2-{3-Butyl-5-oxo-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-[1,2,4]triazol-1-yl}-3-methyl-butyric acid methyl ester 

Relevant articles and documents

Diastereo- And Enantioselective Synthesis of Quaternary α-Amino Acid Precursors by Copper-Catalyzed Propargylation

A diastereo- and enantioselective propargylic substitution reaction between propargylic carbonates and α-substituted nitroacetates catalyzed by a Cu-pybox complex is described. This method allows the preparation of a series of non-proteinogenic quaternary α-amino acid precursors featuring two contiguous stereogenic centers and a terminal alkyne moiety in high yields with good to excellent diastereo- and enantioselectivities in most cases. The propargylated adducts were elaborated into a diverse set of quaternary α-amino acid derivatives.

Stereoselective dehydrobromination of alkyl α-Br α-Cl-carboxylates

(Z)-Alkyl α-Cl-α,β-unsaturated esters are prepared in excellent yields by stereoselective dehydrobromination of alkyl α-Br-α-Cl-carboxylates with LiCl-Li2CO3 in dimethylformamide.