6938-02-9

Basic information

• Product Name: 5,6-dimethoxyquinolin-8-amine
• CAS NO: 6938-02-9
• Molecular Formula: C₁₁H₁₂N₂O₂
• Molecular Weight: 204.2252
• Mol File: 6938-02-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 380.2°C at 760 mmHg
• Flash Point: 183.7°C
• Density: 1.222g/cm³
• Vapor Pressure: 5.55E-06mmHg at 25°C
• Refractive Index: 1.634
• CAS DataBase Reference: 5,6-dimethoxyquinolin-8-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-dimethoxyquinolin-8-amine(6938-02-9)
• EPA Substance Registry System: 5,6-dimethoxyquinolin-8-amine(6938-02-9)

Safety Data

• Hazardous Substances Data: 6938-02-9(Hazardous Substances Data)

Upstream product

• 99069-17-7 4-Acetylamino-1,2-dimethoxy-5-nitrobenzene 
• 7595-31-5 4-amino-5-nitroveratrol 
• 5347-15-9 5-bromo-6-methoxy-8-nitroquinoline 
• 3395-03-7 4,5-dimethoxy-1,2-dinitrobenzene 
• 85-81-4 6-methoxy-8-nitroquinoline 
• 5333-02-8 5,6-dimethoxy-8-nitroquinoline 

Downstream Products

• 132247-40-6 N-(5,6-Dimethoxy-quinolin-8-yl)-benzamide 
• 132247-41-7 4-Chloro-N-(5,6-dimethoxy-quinolin-8-yl)-benzamide 
• 132247-42-8 4-Bromo-N-(5,6-dimethoxy-quinolin-8-yl)-benzamide 
• 132247-43-9 Cyclohexanecarboxylic acid (5,6-dimethoxy-quinolin-8-yl)-amide 
• 17605-76-4 8-(5-isopropylamino-pentylamino)-quinoline-5,6-diol 
• 87321-06-0 5-hydroxy-6-desmethylprimaquine 
• 5423-91-6 N-(5,6-dimethoxy-[8]quinolyl)-hexanediyldiamine 
• 132247-49-5 4-Bromo-N-(5,6-dioxo-5,6-dihydro-quinolin-8-yl)-benzamide 
• 132247-48-4 4-Chloro-N-(5,6-dioxo-5,6-dihydro-quinolin-8-yl)-benzamide 
• 132247-50-8 Cyclohexanecarboxylic acid (5,6-dioxo-5,6-dihydro-quinolin-8-yl)-amide 
• 132247-47-3 N-(5,6-Dioxo-5,6-dihydro-quinolin-8-yl)-benzamide 
• 7505-76-2 N-(5,6-Dioxo-5,6-dihydro-quinolin-8-yl)-acetamide 
• 132247-35-9 8-Ethylamino-quinoline-5,6-dione 
• 49797-49-1 8-Amino-5,6-quinolinedione 

Relevant articles and documents

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HEAT SHOCK PROTEIN 90 INHIBITORS, METHODS OF PREPARING SAME, AND METHODS FOR THEIR USE

Novel classes of molecular chaperone Heat shock protein 90 (Hsp90) inhibitors are disclosed. These compounds are useful in treating and preventing cancer and other Hsp90-related diseases and conditions, such as inflammation and neurodegenerative disorders. Methods of treating and preventing cancer and other Hsp90 related diseases and conditions are disclosed that include administering to the subject a therapeutically effective amount of an Hsp90 inhibitor. Methods of preparing the novel Hsp90 inhibitors are also provided.

Antimalarials. 13. 5-Alkoxy Analogues of 4-Methylprimaquine

A series of nuclear and side-chain analogues of 4-methylprimaquine incorporating an alkoxy group in 5-position of the quinoline nucleus has been prepared.The compounds were tested for suppresive antimalarial activity against Plasmodium berghei in mice and for radical curative antimalarial activity against Plasmodium cynomolgi in the rhesus monkey.Although the toxicity problems characteristic of the 8-aminoquinolines were not overcome, several of the compounds, suprisingly, were highly effective as both blood and tissue schizonticidal agents.