69380-11-6

Basic information

• Product Name: 2-(1-adamantyl)imidazole
• Synonyms: 2-(1-adamantyl)imidazole;1-(1H-Imidazole-1-yl)adamantane;1-(Adamantan-1-yl)-1H-imidazole;1H-Imidazole, 1-tricyclo(3.3.1.13,7)dec-1-yl-
• CAS NO: 69380-11-6
• Molecular Formula: C₁₃H₁₈N₂
• Molecular Weight: 202.3
• Mol File: 69380-11-6.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 364.3°C at 760 mmHg
• Flash Point: 174.1°C
• Appearance: /
• Density: 1.36g/cm³
• Vapor Pressure: 3.56E-05mmHg at 25°C
• Refractive Index: 1.737
• CAS DataBase Reference: 2-(1-adamantyl)imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-adamantyl)imidazole(69380-11-6)
• EPA Substance Registry System: 2-(1-adamantyl)imidazole(69380-11-6)

Safety Data

• Hazardous Substances Data: 69380-11-6(Hazardous Substances Data)

Usage

Derivative of imidazole

Imidazole is a five-membered ring compound containing two nitrogen atoms. 2-(1-adamantyl)imidazole is a derivative of this compound.

Adamantyl group

The adamantyl group is a bulky, hydrophobic substituent that is attached to the imidazole ring in 2-(1-adamantyl)imidazole.

Increased stability and lipophilicity

The presence of the adamantyl group in 2-(1-adamantyl)imidazole increases the stability and lipophilicity of the molecule, making it more suitable for use in medicinal chemistry.

Building block in medicinal chemistry

2-(1-adamantyl)imidazole is a useful building block in the synthesis of pharmaceutical compounds.

Potential applications in drug discovery and development

2-(1-adamantyl)imidazole has potential applications in the field of antiviral and antifungal agents.

Implications in other areas of organic synthesis and material science

The unique structure and properties of 2-(1-adamantyl)imidazole may also have implications in other areas of scientific research and industrial applications.

InChI:InChI=1/C13H18N2/c1-2-15(9-14-1)13-6-10-3-11(7-13)5-12(4-10)8-13/h1-2,9-12H,3-8H2

Upstream product

• 288-32-4 1H-imidazole 
• 768-90-1 1-Adamantyl bromide 
• 24569-89-9 1,3-dehydroadamantane 
• 50-00-0 formaldehyd 
• 768-94-5 1-Adamantanamine 
• 631-61-8 ammonium acetate 
• 281-23-2 adamantane 
• 131543-46-9 Glyoxal 

Downstream Products

• 1016260-28-8 3-(1-adamantyl)-1-[(2-diphenylphosphinoferrocenyl)ethyl]-3H-imidazolium iodide 

Relevant articles and documents

Unexpected Photodegradation of a Phosphaketenyl-Substituted Germyliumylidene Borate Complex

The first zwitterionic borata-bis(NHC)-stabilized phosphaketenyl germyliumylidene [(L2(O=C=P)Ge:] 2 (L2=(p-tolyl)2B[1-(1-adamantyl)-3-yl-2-ylidene]2) has been synthesized by salt-metathesis reaction of [L2

High-thermal-stability and migration-resistant organic light-emitting material as well as preparation method and application thereof

The invention provides a high-thermal-stability and migration-resistant organic luminescent material and a preparation method and application thereof. The structure of the high-thermal-stability and migration-resistant organic luminescent material is [X(M

Synthesis and characterization of gold(I) complexes of dibenzotropylidene-functionalized NHC ligands (Trop-NHCs)

Gold(I) complexes of dibenzotropylidene-functionalized N-heterocyclic carbene ligands (Trop-NHCs) have been prepared in order to investigate their structural features and to reveal possible interactions of the olefin unit with the metal center. The precursor imidazolium chloride salts (R-1) were generated in a single step using N-substituted imidazoles (R = H, Me, DiPP, Ad) and 1 or 2 equiv of Trop-Cl, generating unsymmetrical and symmetrical NHC-olefin hybrids. The structural parameters of the ligands were determined by synthesis and X-ray diffraction analysis of their corresponding gold(I) chloride complexes, revealing highly flexible steric demands of the Trop unit. Conversion of these complexes with halide-abstracting reagents such as AgNTf2 and NaBArF24 cleanly gave neutral, NTf2-coordinated complexes of the type [(NHC)Au(NTf2)] (R-3) and the cationic bis-NHC-coordinated complexes [(NHC)2Au]BArF24 (R-4), respectively. The Gagosz-type complexes R-3 were further tested in the hydration of diphenylacetylene, showing a clear trend in activity depending on the ligand's sensitivity to hydrolysis.