69383-34-2

Upstream product

• 104-51-8 1-butylbenzene 
• 103-80-0 phenylacetyl chloride 
• 6363-21-9 α-ethyldibenzyl ketone 
• 110826-44-3 α-propyldibenzyl ketone 
• 108-88-3 toluene 

Downstream Products

• 64357-44-4 1-(4-butylphenyl)-2-phenylethane-1,2-dione 
• 345318-25-4 3-(4-Butyl-phenyl)-3-hydroxy-4-phenyl-butyric acid ethyl ester 
• 119249-69-3 3-(4-butyl-phenyl)-2,4,5-triphenyl-cyclopentadienone 
• 345312-53-0 3-(4-Butyl-phenyl)-4-phenyl-butyric acid ethyl ester 
• 345290-90-6 3-(4-Butyl-phenyl)-4-phenyl-butyric acid 
• 83787-79-5 3-(4-Butyl-phenyl)-3,4-dihydro-2H-naphthalen-1-one 

Relevant academic research and scientific papers

Benzylic aroylation of toluenes with unactivated tertiary benzamides promoted by directed ortho-lithiation

The deprotonative functionalization of toluenes, for their weak acidity, generally needs strong bases, thus leading to the requirement of harsh conditions and the generation of by-products. Direct nucleophilic acyl substitution reaction of amides with organometallic reagents could provide an ideal solution for ketone synthesis. However, the inert amides and highly reactive organometallic reagents bring great challenges for an efficient and selective synthetic approach. Herein, we reported an lithium diisopropylamide (LDA)-promoted benzylic aroylation of toluenes with unactivated tertiary benzamides, providing a direct and efficient synthesis of various aryl benzyl ketones. This process features a kinetic deprotonative functionalization of toluenes with a readily available base LDA. Mechanism studies revealed that the directed ortho-lithiation of the tertiary benzamide with LDA promoted the benzylic kinetic deprotonation of toluene and triggered the nucleophilic acyl substitution reaction with the amide. [Figure not available: see fulltext.].

Norrish Type I and Type II Reactions of Ketones as Photochemical Probes of the Interior of Zeolites

The Norrish type I and type II reactions of alkylbenzoin ethers, alkyldeoxybenzoins and α-alkyldibenzyl ketones included within the microporous structures of zeolites X and Y have been investigated.Product distributions varied significantly from that observed in benzene.In addition, it differed between various alkali-metal cation-exchanged samples.These variations are interpreted to result from the restriction offered by the zeolite micropores on the motions of the adsorbed organic molecule.Although this study is restricted to ketones, the knowledge gained is expected to be of general value.

MODIFICATION OF PHOTOCHEMICAL REACTIVITY BY ZEOLITES: ROLE OF CATIONS IN CONTROLLING THE BEHAVIOR OF RADICALS GENERATED WITHIN FAUJASITES.

α-Alkyldibenzylketones included in cation exchanged faujasite type zeolites show photobehavior different from that in isotropic organic solvents.Rearrangement and disproportionation which do not contribute in solution are the major processes within the cavities of faujasites.Cation size plays a major role in controlling the pathway pursued by the primary and the secondary radical pair.

Modification of Photochemical Reactivity by Cyclodextrin Complexation: A Remarkable Effect on the Photobehavior of α-Alkyldibenzyl Ketones

The Norrish type I and type II reactions of cyclodextrin-included α-alkyldibenzyl ketones have been investigated in the aqueous solution and in the solid state.The photolysis of solid cyclodextrin complexes led to a single product, diphenylethane (AB), and that of complexes in the aqueous solution resulted in a product arising from the rerrangement of α-alkyldibenzyl ketones.Conformational and super-cage effects are proposed to be responsible for the dramatic alteration observed in the above photobehavior.The difference in the product distribution between solid and solution complexes is attributed to the differences in the restriction imposed by the host on the translational motions of the geminate radical pairs.

Synthesis and Mesomorphic Properties of 2,6-Disubstituted Tetralins

Synthesis and mesomorphic behavior of nine members of each of the two classes of 6-phenyl- and 2-phenyltetralins and five members of the 2-trans-cyclohexyltetralins are reported.The synthesis of one member of each class is described in detail.Besides the target compounds, more than twenty intermediates showed liquid crystalline properties; their transition temperatures are recorded (see Tables 1-6).

Anti-inflammatory agent of benzoyl derivative

Anti-inflammatory agent comprises an active ingredient of benzoyl derivative having the formula STR1 WHEREIN R1 represents hydrogen, halogen, hydroxy, C1-8 alkyl or C1-8 alkoxy, R2 represents hydrogen, halogen,