6363-21-9Relevant articles and documents
Enantioselective 1,4-conjugate addition of diethylzinc to (E)-alkenyl aryl ketones catalysed by Cu/DiPPAM complex
Magrez, Magaly,Wencel-Delord, Joanna,Crévisy, Christophe,Mauduit, Marc
experimental part, p. 3507 - 3511 (2012/06/15)
We report here the use of the DiPPAM-L1 ligand for copper-catalysed asymmetric conjugate addition (ACA) of diethylzinc to various (E)-alkenyl aryl ketones where the aryl ring is either a phenyl group substituted by nitro, chloro or methoxy groups or not s
Biphenol-based phosphoramidite ligands for the enantioselective copper-catalyzed conjugate addition of diethylzinc
Alexakis, Alexandre,Polet, Damien,Rosset, Stephane,March, Sebastien
, p. 5660 - 5667 (2007/10/03)
Phosphoramidite ligands, based on ortho-substituted biphenols and a chiral amine, induce high enantioselectivities (ee's up to 99%) in the copper-catalyzed conjugate addition of dialkylzinc reagents to a variety of Michael acceptors. Particularly, the best reported ee's were obtained for acyclic nitroolefins.
Asymmetric Synthesis of Ketones by SmI2-Mediated Allylation or Benzylation of Ketenes Followed by Enantioselective Protonation
Takeuchi, Seiji,Miyoshi, Norikazu,Ohgo, Yoshiaki
, p. 551 - 554 (2007/10/02)
SmI2-mediated allylation or benzylation of alkylarylketenes followed by enantioselective protonation with α,α'-di-o-xylenedioxide gave the corresponding ketones in 61-91percentee.