69383-68-2

Usage

Uses

Used in Pharmaceutical Industry:
1-CHLORO-2,4-DIMETHYL-5-NITRO-BENZENE is used as a chemical intermediate for the synthesis of various pharmaceuticals, contributing to the development of new medications and therapeutic agents.
Used in Dye Industry:
In the dye industry, 1-CHLORO-2,4-DIMETHYL-5-NITRO-BENZENE serves as an intermediate, playing a crucial role in the production of different types of dyes utilized in coloring textiles, plastics, and other materials.
Used in Agrochemical Industry:
1-CHLORO-2,4-DIMETHYL-5-NITRO-BENZENE is utilized as an intermediate in the synthesis of agrochemicals, which are essential for the development of pesticides and other agricultural products that protect crops and enhance yield.
Used in Organic Synthesis:
1-CHLORO-2,4-DIMETHYL-5-NITRO-BENZENE is employed in organic synthesis, where it acts as a building block for the creation of more complex organic molecules, expanding the scope of chemical research and product development.
Used as a Reagent in Chemical Reactions:
1-CHLORO-2,4-DIMETHYL-5-NITRO-BENZENE functions as a reagent in various chemical reactions, facilitating specific transformations and processes that are vital for the advancement of chemical science and technology.

InChI:InChI=1/C8H8ClNO2/c1-5-3-6(2)8(10(11)12)4-7(5)9/h3-4H,1-2H3

Upstream product

• 95-66-9 2,4-dimethylchlorobenzene 
• 2124-47-2 5-nitro-2,4-dimethylaniline 
• 7647-01-0 hydrogenchloride 
• 1481-68-1 5-chloro-2,4-difluoronitrobenzene 
• 89-69-0 2,4,5-Trichloronitrobenzene 
• 616-72-8 4,6-dinitro-m-xylene 
• 89-87-2 2,4-dimethylnitrobenzene 

Downstream Products

• 69383-63-7 4-Amino-6-chlor-1.3-dimethyl-benzol-2-sulfonsaeure 
• 342045-61-8 4-chloro-6-nitro-isophthalic acid 
• 162100-82-5 2-chloro-5-methyl-4-nitro-benzoic acid 
• 69383-61-5 5-chloro-2,4-dimethylaniline 

Relevant academic research and scientific papers

ISOINDOLINONE COMPOUNDS

Disclosed herein is a compound or pharmaceutically acceptable salts or stereoisomers thereof of of formula I wherein X1 is linear or branched C1-6 alkyl, C3-6 cycloalkyl, -C1-6 alkyl C3-6 cycloalkyl, C6-10 aryl, 5-10 membered heteroaryl, C1-6 alkyl C6-10 aryl, C1-6 alkyl 5-10 membered heteroaryl, wherein X1 is unsubstituted or substituted with one or more of halogen, linear or branched C1-6 alkyl, linear or branched C1-6 heteroalkyl, CF3, CHF2, -O-CHF2, -O-(CH2)2-OMe, OCF3, C1-6 alkylamino, -CN, -N(H)C(O)-C1- 6alkyl, -OC(O)-C1-6alkyl, -OC(O)-C1-4alkylamino, -C(O)O-C1-6alkyl, -COOH, - CHO, -C1-6alkylC(O)OH, -C1-6alkylC(O)O-C1-6alkyl, NH2, C1-6 alkoxy or C1-6 alkylhydroxy; X2 is hydrogen, C6-10 aryl, 5-10 membered heteroaryl, -O-(5-10 membered heteroaryl), 4-8 membered heterocycloalkyl, C1-4 alkyl 4-8 membered heterocycloalkyl, -O-(4-8 membered heterocycloalkyl), -O-C1-4 alkyl-(4-8 membered heterocycloalkyl), -OC(O)-C1-4alkyl-4-8 membered heterocycloalkyl or C6 aryloxy, wherein X2 is unsubstituted or substituted with one or more of linear or branched C1-6 alkyl, NH2, NMe2 or 5-6 membered heterocycloalkyl; n is 0, 1 or 2.

A new route to prepare 6-chloro-5-(2-chloroethyl)oxindole

6-Chloro-5-(2-chloroethyl)oxindole, a key intermediate in the manufacturing of the antipsychotic drug, ziprasidone, has been synthesized by a new route. The salient features of the synthesis are (1) bis-dialkylation of 2,4-difluoro-5-chloronitrobenzene with sodium diethyl malonate, (2) decarboxylative hydrolysis to obtain the oxindole derivative, and (3) reduction and chlorination of acetic ester side chain.

PYRAZINO(AZA)INDOLE DERIVATIVES

Chemical compounds of formula (I): and pharmaceutically acceptable salts and addition compounds and prodrugs thereof are useful in therapy, particularly for the treatment of disorders of the central nervous system; damage to the central nervous system; ca

Bis(dealkoxycarbonylation) of nitroarylmalonates: A facile entry to alkylated nitroaromatics

A simple approach to alkylated nitroaromatics from substituted nitroaryl malonic esters by double decarboxylation is detailed.