89-87-2Relevant articles and documents
Nitration of aromatics with dinitrogen pentoxide in a liquefied 1,1,1,2-tetrafluoroethane medium
Fauziev, Ruslan V.,Kharchenko, Alexandr K.,Kuchurov, Ilya V.,Zharkov, Mikhail N.,Zlotin, Sergei G.
, p. 25841 - 25847 (2021/08/09)
Regardless of the sustainable development path, today, there are highly demanded chemical productions still operating that bear environmental and technological risks inherited from the previous century. The fabrication of nitro compounds, and nitroarenes in particular, is traditionally associated with acidic wastes formed in nitration reactions exploiting mixed acids. However, nitroarenes are indispensable for industrial and military applications. We faced the challenge and developed a greener, safer, and yet effective method for the production of nitroaromatics. The proposed approach comprises the application of an eco-friendly nitrating agent, namely dinitrogen pentoxide (DNP), in the medium of liquefied 1,1,1,2-tetrafluoroethane (TFE) - one of the most non-hazardous Freons. Importantly, the used TFE is not emitted into the atmosphere but is effortlessly recondensed and returned into the process. DNP is obtainedviathe oxidation of dinitrogen tetroxide with ozone. The elaborated method is characterized by high yields of the targeted nitro arenes, mild reaction conditions, and minimal amount of easy-to-utilize wastes.
Method and device for preparing methylnitro-benzene by channelization
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Paragraph 0050; 0051; 0052, (2019/02/04)
The invention discloses a method and a device for preparing methylnitro-benzene by channelization. The device comprises a storage tank, a nitrogen dioxide cylinder, an ozone generator, a flow pump, agas flowmeter, a reaction pipeline filled with a catalyst, a mixing pipeline, two T-shaped mixed joints, a cooling system, a heating system, a back pressure valve and a receiving tank. The method specifically comprises the following steps: opening the cooling system and the heating system; opening the ozone generator; arranging the flow pump and the gas flowmeter; and mixing raw materials liquid methyl benzene and nitrogen dioxide through the first T-shaped mixing joint and feeding the mixture into the mixing pipeline, then mixing the mixture with ozone in the second T-shaped mixing joint, feeding the mixture into the reaction pipeline filled with the catalyst for a nitrifying reaction, and post-treating a reaction liquid to obtain methylnitro-benzene. The method is controlled precisely and automatically, and is simple to operate, mild in reaction condition, simple in post treatment, quick to transfer mass and heat, high in safety and good in economical benefit.
Regioselective nitration of m-xylene catalyzed by zeolite catalyst
Dong, Xiongzi,Peng, Xinhua
, p. 1122 - 1128 (2016/01/15)
Nitration with nitric acid and acetic anhydride via acetyl nitrate as nitrating species is efficient with the substrate m-xylene as solvent. Zeolite Hβ with an SiO2/Al2O3 ratio of 500 was found to be the most active of the catalysts tried both in yield and regioselectivity in the nitration of m-xylene. The molecular volume of the reactants was calculated with the Gaussian 09 program at the B3LYP/6-311+G(2d, p) level and compared with the size of the zeolite Hβ channels. A range of other substrates were subjected to the nitrating system under the same conditions as those optimized for m-xylene and excellent selectivity was obtained.
