69390-19-8Relevant articles and documents
Curcumin inspired synthesis of unsymmetrical diarylpentanoids with highly potent anti-parasitic activities:: In silico studies and DFT-based stereochemical calculation
Din, Zia Ud,Santos, Alef Dos,Trapp, Marilia Almeida,Lazarin-Bidóia, Danielle,Garcia, Francielle Pelegrin,Peron, Francieli,Nakamura, Celso Vataru,Rodrigues-Filho, Edson
, p. 820 - 831 (2016)
Unsymmetrical diarylpentanoid analogues of curcumin have been synthesized by Claisen-Schmidt condensation of different aldehydes and ketones. Anisaldehyde treated with 2-butanone and chlorobenzaldehyde with 2-pentanone resulted in intermediate compounds 1
Decarboxylation-triggered homo-Nazarov cyclization of cyclic enol carbonates catalyzed by rhenium complex
Kimaru, Natsuki,Komatsuki, Keiichi,Saito, Kodai,Yamada, Tohru
supporting information, p. 6133 - 6136 (2021/06/30)
Decarboxylative homo-Nazarov cyclization catalyzed by a Lewis acid was achieved using a cyclic enol carbonate bearing a cyclopropane moiety as a substrate. Various substrates were converted into the corresponding multi-substituted cyclohexenones in good yieldsviadecarboxylation, followed by 6-membered ring formation involving cyclopropane-ring-opening.
Thermal decarboxylative Nazarov cyclization of cyclic enol carbonates involving chirality transfer
Kozuma, Akane,Komatsuki, Keiichi,Saito, Kodai,Yamada, Tohru
supporting information, p. 60 - 63 (2019/12/12)
Decarboxylative Nazarov cyclization of chiral cyclic enol carbonates proceeded to afford chiral 2-cyclopentenones with excellent chirality transfer under thermal conditions without any catalyst. Interestingly, the thermal decarboxylative Nazarov cyclization furnished the desired product with better chirality transfer than the Lewis acid-catalyzed reaction.
