694-34-8Relevant academic research and scientific papers
Fluorinated cyclopropanecarboxylic acids and their derivatives
Gassen,Baasner
, p. 127 - 139 (2007/10/02)
The addition of halofluorocarbenes such as :CF2, :CClF or :CBrF, generated from the appropriate halofluoromethanes with bases, to butadiene or isoprene gives the corresponding l-vinyl substituted halofluorocyclopropanes in moderate to good yield. The vinyl group facilitates the carbene addition and permits a subsequent wide derivatisation. Several transformations including hydroboration, oxidation and Curtius degradation are presented. Furthermore, replacement of the chlorine atom in 2-chloro-2-fluorocyclopropanecarboxylic acid derivatives by hydrogen is achieved catalytically with Raney nickel. This sequence provides a convenient route to mono-fluorine substituted cyclopropane carboxylic acids.
THE THERMAL DEAZETATIONS OF FLUORINATED 2,3-DIAZABICYCLOHEPT-2-ENES
Dolbier, William R.,Al-Pekri, Dheya M.
, p. 39 - 44 (2007/10/02)
Thermal deazetation of difluoro- and tetrafluoro-2,3-diazabicyclohept-2-enes proceed via two parallel mechanistic pathways, one involving formation of a diradical via simple N2 loss, and the other proceeding via a retro-dipolar cycloaddition process.A key finding was the absence of isolation of a bicyclopentane product in the difluoro case.
