69408-82-8 Usage
Uses
Used in Biological and Chemical Research:
3-Amino-N-(2-diethylaminoethyl)-1,8-naphthalimide serves as a fluorescent probe for various applications, including cell staining, protein labeling, and the detection of molecular interactions. Its fluorescent properties allow for the specific targeting and visualization of biological molecules and cellular processes, providing researchers with a powerful tool for studying complex biological and chemical systems.
Used in Cell Staining:
In the field of cell biology, 3-Amino-N-(2-diethylaminoethyl)-1,8-naphthalimide is utilized as a fluorescent stain to label and visualize cellular components. Its ability to bind specifically to certain structures enables researchers to track and monitor cellular processes with high precision.
Used in Protein Labeling:
3-Amino-N-(2-diethylaminoethyl)-1,8-naphthalimide is employed as a protein label in biochemistry, allowing for the tracking of protein movement, localization, and interactions within biological systems. This labeling is crucial for understanding protein dynamics and their roles in cellular functions.
Used in Detecting Molecular Interactions:
3-Amino-N-(2-diethylaminoethyl)-1,8-naphthalimide is also used to detect and study interactions between different molecules within biological systems. Its fluorescent properties make it an ideal tool for observing binding events, conformational changes, and other molecular dynamics that are not visible under normal conditions.
Overall, 3-Amino-N-(2-diethylaminoethyl)-1,8-naphthalimide is a versatile and essential tool in advancing our understanding of biological and chemical processes, with applications spanning across various scientific disciplines.
Check Digit Verification of cas no
The CAS Registry Mumber 69408-82-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,4,0 and 8 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 69408-82:
(7*6)+(6*9)+(5*4)+(4*0)+(3*8)+(2*8)+(1*2)=158
158 % 10 = 8
So 69408-82-8 is a valid CAS Registry Number.
InChI:InChI=1/C18H21N3O2/c1-3-20(4-2)8-9-21-17(22)14-7-5-6-12-10-13(19)11-15(16(12)14)18(21)23/h5-7,10-11H,3-4,8-9,19H2,1-2H3
69408-82-8Relevant academic research and scientific papers
Design, antiviral and cytostatic properties of isoxazolidine-containing amonafide analogues
Kokosza, Kamil,Andrei, Graciela,Schols, Dominique,Snoeck, Robert,Piotrowska, Dorota G.
, p. 3135 - 3146 (2015/08/03)
Abstract A novel series of 5-arylcarbamoyl- and 5-arylmethyl-2-methylisoxazolidin-3-yl-3-phosphonates have been synthesized via cycloaddition of N-methyl-C-(diethoxyphosphoryl)nitrone with N-substituted naphthalimide acrylamides and N-allylnaphthalimides. All cis- and trans-isoxazolidine phosphonates obtained herein were assessed for antiviral activity against a broad range of DNA and RNA viruses. Isoxazolidines trans-9d and trans-9f exhibited the highest activity (EC50 = 8.9 μM) toward cytomegalovirus. Compounds cis- and trans-9d as well as cis- and trans-9f were found potent against HSV and Vaccinia viruses (EC50 in the 45-58 μM range), whereas isoxazolidines 10a and 10d suppressed replication of Coxsackie B4 and Punta Toro viruses (EC50 in the 45-73 μM range). Antiproliferative evaluation of all obtained isoxazolidines revealed the promising activity of cis-9b, cis-9d, trans-9d, cis-9e, trans-9e, cis-9f and trans-9f toward tested cancer cell lines with IC50 in the 1.1-19 μM range.
