69438-62-6

Upstream product

• 80234-04-4 2-phenylacrylaldehyde diethyl acetal 
• 58189-55-2 2,2-Dibrom-1-vinyl-1-phenyl-cyclopropan 
• 156020-82-5 2,2-dibromo-1-phenylcyclopropanecarbaldehyde diethylacetal 

Downstream Products

• 22174-59-0 (3-methoxyprop-1-yn-1-yl)benzene 
• 55563-72-9 3-methoxy-1-phenylpropan-1-one 
• 178619-02-8 4-bromo-3-phenyl-2(5H)-furanone 
• 29417-89-8 1-methoxy-3-phenyl-2-propanone 
• 768-03-6 Phenyl vinyl ketone 
• 195623-20-2 1-(2,2-dibromo-1-phenylcyclopropyl)-3-buten-1-ol 
• 69438-60-4 2,2-dibromo-1-phenyl-cyclopropanecarbaldehyde 
• 37828-71-0 1-phenyl-3-isopropoxy-1-propyne 
• 85670-60-6 3-isopropoxy-1-phenyl-1-propanone 
• 67074-45-7 2,2-dibromo-1-phenylcyclopropylmethanol 

Relevant academic research and scientific papers

Reactions of 2,2-dibromocyclopropyl carboxylic acids with methyllithium

For reactions of 2,2-dibromocyclopropyl carboxylic acids with methyllithium, the course reaction depends mainly on the position of the carboxyl group.When the COOH group is directly attached to the gem-dibromocyclopropane ring MeLi generally attacks the gem-dibromo moiety and gives the corresponding monobromocyclopropane as the principal product.When the reaction is performed above -80 deg C the monobromides are formed stereospecifically in the trans configuration.The highest yields, as high as 80-90percent, are obtained 0 deg C.When the carboxyl group is not directly attached to the cyclopropane ring most of the MeLi is consumed in an acid-base reaction with the COOH group.