69446-62-4Relevant academic research and scientific papers
Electro-oxidative C(sp2)-H/O-H cross-dehydrogenative coupling of phenols and tertiary anilines for diaryl ether formation
Tang, Hongyang,Smolders, Simon,Li, Yun,De Vos, Dirk,Vercammen, Jannick
, p. 3925 - 3930 (2021/06/18)
The formation of diaryl ethers is generally achievedviatransition metal catalyzed etherification reactions (Ullmann, Chan-Lam, Buchwald-Hartwig) with prefunctionalized aryl halide substrates at elevated temperatures. Herein, we report a protocol for electrochemical C(sp2)-H/O-H cross-dehydrogenative coupling of phenols and tertiary anilines to synthesize diaryl ethers. The C(sp2) H/O-H coupling product can be obtained under metal- and oxidant-free conditions at room temperature in moderate to excellent yield (up to 83% yield) with high regioselectivity (>99% forpara-substitution) and with a broad substrate scope (22 examples).
Study on the structure-activity relations of brominated hydroxy diphenyl ethers derivatives with anilines
Luo, Bin,Zhou, Hua-Hong,Yu, Kang-Kang,Wu, Kai-Qun,Chen, Tian,Wang, Yu-Liang
, p. 3863 - 3866 (2013/05/08)
In order to study the influence of anilines on antibacterial activity, eight novel brominated hydroxy diphenyl ethers derivatives were designed and synthesized. The antibacterial activities of the new compounds were tested via agar-well diffusion method in vitro under different concentrations. The results showed the derivatives had antibacterial activities at the concentration 50 μg/mL against Staphylococcus aureus SC and Staphylococcus aureus ATCC26112.
Correlation between molecular dipole moment and centrosymmetry in some crystalline diphenyl ethers
Dey, Archan,Desiraju, Gautam R.
, p. 2486 - 2488 (2007/10/03)
The presence of a large molecular dipole moment in diphenyl ethers leads unequivocally to a centrosymmetric crystal structure. The Royal Society of Chemistry 2005.
