6946-96-9

Usage

Uses

Used in Pharmaceutical Industry:
2-(4-methoxyphenoxy)-N-4-[5-(1-methylethyl)-1,3-benzoxazol-2-yl]phenylacetamide is used as a pharmaceutical compound for its potential therapeutic applications. Its unique structure allows it to interact with biological targets, making it a candidate for the development of new drugs.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 2-(4-methoxyphenoxy)-N-4-[5-(1-methylethyl)-1,3-benzoxazol-2-yl]phenylacetamide is utilized for the design and synthesis of novel molecules with potential therapeutic effects. Its structural features can be exploited to create new drug candidates with improved pharmacological properties.
Used in Materials Science:
2-(4-methoxyphenoxy)-N-4-[5-(1-methylethyl)-1,3-benzoxazol-2-yl]phenylacetamide is employed in materials science for the development of advanced materials with specific properties. Its unique structure can contribute to the creation of materials with tailored characteristics for various applications, such as sensors, optoelectronics, or nanotechnology.

Upstream product

• 2622-50-6 butyl-tetrahydropyran-2-yl-amine 
• 110-87-2 3,4-dihydro-2H-pyran 
• 109-73-9 N-butylamine 
• 64-17-5 ethanol 
• 7647-01-0 hydrogenchloride 
• 694-54-2 tetrahydro-2H-2-pyranol 
• 542-28-9 3,4,5,6-tetrahydro-2H-pyran-2-one 
• 1225517-96-3 N-butyl-5-hydroxypentanamide 

Downstream Products

• 4789-08-6 1-Butyl 2-Piperidinone 
• 6945-47-7 5-Dibutylamino-1-pentanol 

Relevant academic research and scientific papers

Copper-Catalyzed Functionalizations of C60 with Amino Alcohols

CuI-catalyzed diverse functionalizations of C60 with amino alcohols with aerobic oxygen as the sole oxidant have been explored. For 2-/3-amino alcohols, an aminooxygenation reaction occurs to generate fulleromorpholine and fullerooxazepane derivatives. When a tethered furan ring exists, a further intramolecular [4 + 2] reaction with the neighboring double bond occurs to furnish the cis-1 products. In the case of 4-/5-amino alcohols, methanofullerenes linking with cyclic amides are obtained through cyclic enamine intermediates.

Reductive hydroxyalkylation/alkylation of amines with lactones/esters

We have developed a one-pot method for the direct intermolecular reductive hydroxyalkylation or alkylation of amines using lactones or esters as the hydroxyalkylating/alkylating reagents. The method is based on the in situ amidation of lactones/esters with DIBAL-H-amine complex (for primary amines) or DIBAL-H-amine hydrochloride salt complex (for secondary amines), followed by reduction of the amides with an excess of DIBAL-H. Different from the reduction of Weinreb amides with DIBAL-H where aldehydes are formed, the reduction of the in situ formed Weinreb amides yielded amines. Moreover, this method is not limited to Weinreb amides, instead, it also works for other amides in general. A plausible mechanism is suggested to account for the outcome of the reactions.

Addition-Rearrangement Reactions of N-(Arylsulphonyloxy)amines and 3,4-Dihydro-2H-pyran

A series of N-alkyl-O-(arylsulphonyl)hydroxylamines (NSA) was treated with 3,4-dihydro-2H-pyran (DHP).Acid-catalysed addition to the double bond followed by cationic rearrangement gave cyclic imidates from hydride migration (major) and ring expansion (min