6947-10-0

Basic information

• Product Name: dipropyl 2-hydroxybutanedioate
• Synonyms: Dipropyl malate; Malic acid, dipropyl ester
• CAS NO: 6947-10-0
• Molecular Formula: C₁₀H₁₈O₅
• Molecular Weight: 218.2469
• Mol File: 6947-10-0.mol

Chemical Properties

• Boiling Point: 313.4°C at 760 mmHg
• Flash Point: 114.3°C
• Density: 1.099g/cm³
• Vapor Pressure: 4.32E-05mmHg at 25°C
• Refractive Index: 1.45
• CAS DataBase Reference: dipropyl 2-hydroxybutanedioate(CAS DataBase Reference)
• NIST Chemistry Reference: dipropyl 2-hydroxybutanedioate(6947-10-0)
• EPA Substance Registry System: dipropyl 2-hydroxybutanedioate(6947-10-0)

Safety Data

• Hazardous Substances Data: 6947-10-0(Hazardous Substances Data)

Upstream product

• 71-23-8 propan-1-ol 
• 97-67-6 (S)-Malic acid 
• 617-48-1 malic acid 

Relevant articles and documents

Retention Characteristics and Sorption Enthalpies of Esters of Natural Hydroxycarboxylic Acids on DB-1 Stationary Phase

Abstract: Sorption characteristics and retention of esters of glycolic, lactic, malic, and tartaric acids with C1?C8 alcohols of linear structure are studied by gas-liquid chromatography in the temperature range of 90?260°C on DB-1 nonpolar phase. The values of the retention indices of the compounds studied are obtained. On the basis of experimentally determined retention times, the thermodynamic characteristics of sorption under the conditions of limiting dilution are estimated. The dependences of the change in sorption enthalpies on the length of the linear alkyl substituent and on the value of the logarithmic retention index are found. The possibility of estimating the energy of intermolecular interactions of lactic acid esters in the liquid phase is shown on the basis of the obtained values of sorption enthalpies and vaporization enthalpies.

Enantiomerically pure tetrahydro-5-oxo-2-furancarboxylic esters from dialkyl 2-oxoglutarates

Enantiomerically pure tetrahydro-5-oxo-2-furancarboxylic esters can be prepared either by enzymatic resolution of the racemic γ-lactones themselves or by bioreduction with baker's yeast of dialkyl 2-oxoglutarates and subsequent cyclization of the resulting dialkyl 2-hydroxyglutarates. The best results were obtained by the former route, by which the desired compounds were isolated in high enantiomeric excess. Bioreductions were less satisfactory. In fact the hydroxyester intermediates were initially formed as racemic mixtures and their final enantiomeric enrichment was reached by asymmetric destruction, occurring in the bioreaction medium, however at the same time large amounts of alkyl 4-hydroxybutanoates were formed as side products.

A facile conversion of halides, alcohols and olefins to esters using iron(III) perchlorate

A facile method has been developed for the esterification of halides/alcohols/olefins with carboxylic acids using iron(III) perchlorate.