69480-06-4

Usage

Uses

Used in Organic Chemistry:
Ethanone, 1-(2,6-dihydroxy-4-methoxy-3-methylphenyl)is used as a chemical intermediate for the synthesis of various organic compounds, leveraging its unique structure and reactivity.
Used in Pharmaceutical Research:
Ethanone, 1-(2,6-dihydroxy-4-methoxy-3-methylphenyl)is utilized in pharmaceutical research as a potential building block for the development of new drugs or health supplements, owing to its antioxidant properties and the presence of functional groups that can be further modified or exploited in drug design.
Used in Antioxidant Formulations:
Ethanone, 1-(2,6-dihydroxy-4-methoxy-3-methylphenyl)is used as an antioxidant in various formulations, such as health supplements and nutraceuticals, to provide protection against oxidative stress and support overall health.
Used in Chemical Synthesis Industry:
In the chemical synthesis industry, Ethanone, 1-(2,6-dihydroxy-4-methoxy-3-methylphenyl)- serves as a key intermediate for the production of specialty chemicals, fine chemicals, and other complex organic molecules, contributing to the development of innovative products and materials.

Upstream product

• 55382-24-6 5-methoxy-4-methyl-resorcinol 
• 75-05-8 acetonitrile 
• 2657-28-5 2,4,6-trihydroxy-3-methyl-acetophenon 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 88-03-9 2,4,6-trihydroxytoluene 
• 39548-93-1 1-(6-benzyloxy-2,4-dihydroxy-3-methyl-phenyl)-ethanone 
• 74-88-4 methyl iodide 
• 497949-65-2 3-formyl-2,6-dihydroxy-4-methoxy-acetophenone 
• 39828-28-9 2,6-Dihydroxy-4-methoxy-3-methyl-benzoesaeure-methylester 
• 487-70-7 2,4,6-trihydroxybenzaldehyde 
• 109089-86-3 1-(6-benzyloxy-2-hydroxy-4-methoxy-3-methyl-phenyl)-ethanone 

Downstream Products

• 98569-63-2 1,1'-(methylenebis(2,6-dihydroxy-4-methoxy-5-methyl-3,1-phenylene))bis(ethan-1-one) 
• 109469-69-4 5-hydroxy-7-methoxy-2-(4-methoxy-phenyl)-8-methyl-chroman-4-one 
• 916987-32-1 3-acetyl-2,4-dihydroxy-6-methoxy-5-methylbenzaldehyde 
• 916987-34-3 2-hydroxy-3-acetyl-4-benzoxy-5-methyl-6-methoxybenzaldehyde 
• 1417701-55-3 1-(3-(3-acetyl-2,4-dihydroxy-6-methoxy-5-(3-methylbut-2-en-1-yl)benzyl)-2,6-dihydroxy-4-methoxy-5-methylphenyl)ethan-1-one 
• 1417701-56-4 1,1'-(methylenebis(2,6-dihydroxy-4-methoxy-5-(3-methylbut-2-en-1-yl)-3,1-phenylene))bis(ethan-1-one) 
• 857554-28-0 (2-acetyl-3-hydroxy-5-methoxy-4-methyl-phenoxy)-acetic acid 
• 3133-39-9 1,3-diacetyl-2,4,6-trimethoxy-5-methyl-benzene 
• 3098-39-3 2,4-diacetyl-5-methoxy-6-methyl-resorcinol 

Relevant academic research and scientific papers

Mallotojaponins B and C: Total Synthesis, Antiparasitic Evaluation, and Preliminary SAR Studies

(Chemical Equation Presented). The first total syntheses of mallotojaponin B and C as well as several analogues have been achieved. Biological evaluation of the synthesized compounds against Plasmodium falciparum and Trypanosoma brucei have also been carried out.

Concise synthesis and cellular evaluation of 3′-formyl-4′,6′-dihydroxy-2′-methoxy-5′-methylchalcone (FMC) and its analogues

3′-Formyl-4′,6′-dihydroxy-2′-methoxy-5′-methylchalcone (FMC) was a natural product isolated from Cleistocalyx operculatus. A four-step synthetic strategy toward FMC and its four analogues (1b-1e) was first developed. All compounds were synthesized from commercially available 2,4,6-trihydroxyacetophenone; formylation at 3′ position under Vilsmeier-Haack conditions was followed by the introduction of a methyl group at 5′ position. The key step of selective methylation at 2′ position was achieved by trimethylsilyldiazomethane (TMSCHN2). Then substituted aromatic aldehydes were condensed through Claisen-Schmidt reaction in the presence of potassium hydroxide. All structures were confirmed by 1H NMR, 13C NMR, and high-resolution mass spectra. FMC and analogues were screened for their antiproliferative activity.

Anti-AIDS agents 68. The first total synthesis of a unique potent anti-HIV chalcone from genus Desmos

The first total synthesis of a unique highly functionalized and potent anti-HIV chalcone 1, isolated from genus Desmos, was achieved from commercially available 2,4,6-trihydroxytoluene (3) or 2,4,6-trihydroxybenzaldehyde (2) in five (from 3) or six steps (from 2).