695-19-2

Usage

Uses

Used in Chemical Catalysts:
1-Methyl-4(1H)-pyridinone is used as a catalyst in acylation reactions for enhancing the efficiency and selectivity of these processes. Its ability to stabilize transition states and facilitate bond formation makes it a valuable component in various organic synthesis applications.
Used in Pharmaceutical and Agrochemical Industries:
In the preparation of phosphorus-containing thiosemicarbazides, 1-Methyl-4(1H)-pyridinone serves as a key intermediate. These thiosemicarbazides are important due to their potential applications as antimicrobial, antiviral, and antitumor agents, as well as their use in the development of new pesticides and agrochemicals.
Overall, 1-Methyl-4(1H)-pyridinone is a versatile compound with significant applications in the fields of catalysis and the synthesis of biologically active molecules, making it an important substance for both research and industrial applications.

InChI:InChI=1/C6H7NO/c1-7-4-2-6(8)3-5-7/h2-5H,1H3

Upstream product

• 13441-45-7 N-methyl-4-cyanopyridinium 
• 2301-80-6 N-methyl-4-methylpyridinium iodide 
• 186581-53-3 diazomethane 
• 620-08-6 4-methoxypyridine 
• 127427-45-6 2-bromo-2,2-difluoro-N-phenyl-acetamide 

Downstream Products

• 106-52-5 N-methyl-4-hydroxypiperidine 
• 6887-59-8 1-methylpyridine-4(1H)-thione 
• 99794-26-0 2-(2-hydroxymethylbenzoyl)-1-methyl-4-pyridone 
• 99794-27-1 cyclic hemiacetal 
• 99794-23-7 2-(2-carboxyphenylcarbonyl)-1-methyl-4-pyridone 
• 115177-86-1 2-hydroxydiphenylmethyl-1-methyl-4-pyridone 
• 99794-20-4 2-benzyl-1-methyl-4-pyridone 
• 99794-25-9 1-methyl-2-(1,2-diphenylethyl)-4-pyridone 
• 99794-21-5 2-(1-hydroxyphenylmethyl)-1-methyl-4-pyridone 
• 99794-22-6 2-benzoyl-1-methyl-4-pyridone 
• 35488-00-7 1-methyl-2,3-dihydro-4-pyridone 
• 53589-02-9 1-methyl-4-(4-nitro-benzoyloxy)-piperidine 
• 760-67-8 2-ethylhexanoic acid chloride 
• 33445-17-9 cyclohexyl-hydroxy-phenyl-acetic acid-(1-methyl-[4]piperidyl ester) 

Relevant academic research and scientific papers

Slicing and Splicing of Bromodifluoro-N-arylacetamides: Dearomatization and Difunctionalization of Pyridines

Copper-catalyzed dearomatization and difunctionalization of pyridines have been disclosed, in which bromodifluoro-N-arylacetamide was sliced into five fragments and three or four of them were transferred to pyridine partners. Through this reaction, novel N-difluoromethyl-2-imine dihydropyridine derivatives can be conveniently accessed from commercially available 4-amino substituted pyridines. This strategy demonstrates a novel fluorination method featuring high atom economy, environmental friendliness, an easily available catalyst, and simple operation.

Variation of Counterion Binding in Micelles of Cetyltrimethylammonium Hydroxide

Reaction of N-methyl-4-cyanopyridinium fluoroborate (1) with OH- in aqueous micelles of cetyltrimethylammonium hydroxide (CTAOH) occurs wholly in the aqueous pseudophase.Comparison of the rate constants in CTAOH and NaOH allows estimation of the concentrations of free and micellar bound OH-.The values of α, the fractional ionization of the micelles, decrease with increasing concentration of OH-, in agreement with evidence from reactions of substrates bound to micelles of CTAOH.

2- and 4-Pyridones by Oxidative Demethylation of 2- and 4-Methylpyridinium Cations

1-Substituted-2- and -4-methylpyridinium cations are converted by pentyl or ethyl nitrite and sodium methoxide into 1-substituted-2- and -4-pyridones respectively.