69504-14-9 Usage
General Description
3'-O-tert-Butyldimethylsilyladenosine is a chemical compound that belongs to the class of adenosine derivatives. It is a modified form of adenosine, which is a nucleoside that plays a crucial role in various biological processes. 3'-O-tert-Butyldimethylsilyladenosine has a tert-butyldimethylsilyl (TBDMS) group attached to the 3'-hydroxyl (OH) position of adenosine. The presence of the TBDMS group provides protection to the 3'-OH group, which can be useful in chemical synthesis and various biological applications. The modification of adenosine at this position can alter its biological activity and stability, making 3'-O-tert-Butyldimethylsilyladenosine a valuable tool in research and pharmaceutical development.
Check Digit Verification of cas no
The CAS Registry Mumber 69504-14-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,5,0 and 4 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 69504-14:
(7*6)+(6*9)+(5*5)+(4*0)+(3*4)+(2*1)+(1*4)=139
139 % 10 = 9
So 69504-14-9 is a valid CAS Registry Number.
69504-14-9Relevant articles and documents
Chemoselective deprotection of triethylsilyl ethers
Chandra, Tilak,Broderick, William E.,Broderick, Joan B.
, p. 1016 - 1029 (2009)
An efficient and selective method was developed for the deprotection of triethylsilyl (TES) ethers using formic acid in methanol (5-10%) or in methylene chloride 2-5%) with excellent yields. TES ethers are selectively deprotected to the corresponding alco
ISOMERIZATION OF tert-BUTYLDIMETHYLSILYL PROTECTING GROUPS IN RIBONUCLEOSIDES
Ogilvie, Kelvin K.,Entwistle, Douglas W.
, p. 203 - 210 (2007/10/02)
The tert-butyldimethylsilyl group undergoes isomerization between O-2' and O-3' in ribonucleosides in solution.Isomerization is most rapid in protic solvents and extremely slow in such solvents as dry dimethyl sulfoxide, pyridine, oxolane, chloroform, or
