69504-03-6

Basic information

• Product Name: 3',5'-bis-O-(tert-butyldimethylsilyl)-β-D-adenosine
• Synonyms: 3',5'-bis-O-(tert-butyldimethylsilyl)-β-D-adenosine
• CAS NO: 69504-03-6
• Molecular Weight: 495.77
• Mol File: 69504-03-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3',5'-bis-O-(tert-butyldimethylsilyl)-β-D-adenosine(CAS DataBase Reference)
• NIST Chemistry Reference: 3',5'-bis-O-(tert-butyldimethylsilyl)-β-D-adenosine(69504-03-6)
• EPA Substance Registry System: 3',5'-bis-O-(tert-butyldimethylsilyl)-β-D-adenosine(69504-03-6)

Safety Data

• Hazardous Substances Data: 69504-03-6(Hazardous Substances Data)

Upstream product

• 81691-32-9 N⁶-benzoyl-2',5'-bis-O-(tert-butyldimethylsilyl)adenosine 

Downstream Products

• 109923-56-0 N⁶0-(4,4'-dimethoxytrityl)-2'-O-tosyladenosine 
• 10414-81-0 2'-amino-2'-deoxyadenosine 
• 58699-61-9 2'-Azido-2'-deoxyadenosine 
• 137091-53-3 6-N,N-dibenzoyl-9-(3-O-(tert-butyldimethylsilyl)-2-deoxy-2-methylene-5-O-(p-toluenesulfonyl)-β-D-erythro-pentofuranosyl)adenine 
• 137058-89-0 C₂₅H₂₅N₅O₇S₂ 
• 137058-84-5 6-N,N-dibenzoyl-9-(3-O-(tert-butyldimethylsilyl)-2,5-dideoxy-5-iodo-2-methylene-β-D-erythro-pentofuranosyl)adenine 
• 137058-83-4 Toluene-4-sulfonic acid (2R,3S,5R)-5-(6-amino-purin-9-yl)-3-(tert-butyl-dimethyl-silanyloxy)-4-methylene-tetrahydro-furan-2-ylmethyl ester 
• 137058-82-3 9-(2-deoxy-2-methylene-5-O-(p-toluenesulfonyl)-β-D-erythro-pentofuranosyl)adenine 
• 104409-41-8 2'-deoxy-2'-methyleneadenosine 
• 201677-02-3 1',2'-didehydro-2'-deoxy-3',5'-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-N⁷-triphenylphosphoranylideneadenosine 
• 685870-97-7 N-benzoyl-N-{9-[4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-3-hydroxy-3-(1-methoxy-vinyl)-tetrahydro-furan-2-yl]-9H-purin-6-yl}-benzamide 
• 685870-95-5 6-N,N-dibenzoyl-3',5'-di-O-(tert-butyldimethylsilyl)-adenosine 
• 685870-96-6 6-N,N-dibenzoyl-3',5'-di-O-(tert-butyldimethylsilyl)-2'-oxo-adenosine 
• 58-61-7 adenosine 

Relevant articles and documents

ISOMERIZATION OF tert-BUTYLDIMETHYLSILYL PROTECTING GROUPS IN RIBONUCLEOSIDES

The tert-butyldimethylsilyl group undergoes isomerization between O-2' and O-3' in ribonucleosides in solution.Isomerization is most rapid in protic solvents and extremely slow in such solvents as dry dimethyl sulfoxide, pyridine, oxolane, chloroform, or