695191-37-8Relevant articles and documents
2-Phenyl-1 H-pyrrole-3-carboxamide as a New Scaffold for Developing 5-HT6Receptor Inverse Agonists with Cognition-Enhancing Activity
Drop, Marcin,Canale, Vittorio,Chaumont-Dubel, Séverine,Kurczab, Rafa?,Sata?a, Grzegorz,Bantreil, Xavier,Walczak, Maria,Koczurkiewicz-Adamczyk, Paulina,Latacz, Gniewomir,Gwizdak, Anna,Krawczyk, Martyna,Go??biowska, Joanna,Grychowska, Katarzyna,Bojarski, Andrzej J.,Nikiforuk, Agnieszka,Subra, Gilles,Martinez, Jean,Paw?owski, Maciej,Popik, Piotr,Marin, Philippe,Lamaty, Frédéric,Zajdel, Pawe?
, p. 1228 - 1240 (2021/04/07)
Serotonin type 6 receptor (5-HT6R) has gained particular interest as a promising target for treating cognitive deficits, given the positive effects of its antagonists in a wide range of memory impairment paradigms. Herein, we report on degradation of the
2-Trimethylsilylethanesulfonyl (SES) versus tosyl (Ts) protecting group in the preparation of nitrogen-containing five-membered rings. A novel route for the synthesis of substituted pyrrolines and pyrrolidines
Declerck, Valerie,Allouchi, Hassan,Martinez, Jean,Lamaty, Frederic
, p. 1518 - 1521 (2007/10/03)
(Chemical Equation Presented) The 2-trimethylsilylethanesulfonyl (or SES) protecting group was compared to the tosyl (Ts) group in the preparation of a nitrogen-containing five-membered ring obtained by the aza-Baylis - Hillman/alkylation/RCM route. While
