807624-15-3

Usage

Chemical class

Pyrrole carboxylic acids 1H-Pyrrole-3-carboxylic acid, 2-phenyl- belongs to a class of organic compounds that contain a pyrrole ring and a carboxylic acid group.

Structural components

Pyrrole ring, carboxylic acid, and phenyl group The compound consists of a five-membered nitrogen-containing pyrrole ring, a carboxylic acid group (-COOH), and a phenyl group (-C6H5).

Pharmaceutical applications

Building block for synthesis 1H-Pyrrole-3-carboxylic acid, 2-phenylhas been studied for its potential use as a building block in the synthesis of various biologically active molecules, making it a valuable compound in drug discovery and development.

Anti-inflammatory properties

Reducing inflammation 1H-Pyrrole-3-carboxylic acid, 2-phenyl- has been found to exhibit anti-inflammatory properties, which may be useful in the treatment of conditions characterized by inflammation.

Antioxidant properties

Neutralizing free radicals 1H-Pyrrole-3-carboxylic acid, 2-phenylalso shows antioxidant properties, which can help protect cells from damage caused by free radicals and may be beneficial in treating various diseases and conditions.

Potential therapeutic uses

Treatment of various diseases and conditions Due to its anti-inflammatory and antioxidant properties, 1H-Pyrrole-3-carboxylic acid, 2-phenyl- has been investigated for its potential use in treating a range of diseases and conditions, although further research is needed to determine its efficacy and safety in clinical settings.

Upstream product

• 38597-58-9 2-phenyl-1H-pyrrole-3-carboxylic acid ethyl ester 
• 100-52-7 benzaldehyde 
• 125151-82-8 methyl α-methylene-β-[(p-toluenesulfonyl)amino]-3-phenylpropionate 
• 695191-37-8 methyl-2-{[(N-allyl-4-methylphenyl)sulfonamido](phenyl)methyl}acrylate 
• 190272-32-3 methyl 2-phenyl-1-tosyl-2,5-dihydro-1H-pyrrole-3-carboxylate 
• 52179-69-8 methyl 2-phenyl-1H-pyrrole-3-carboxylate 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 

Relevant academic research and scientific papers

2-Phenyl-1 H-pyrrole-3-carboxamide as a New Scaffold for Developing 5-HT6Receptor Inverse Agonists with Cognition-Enhancing Activity

Serotonin type 6 receptor (5-HT6R) has gained particular interest as a promising target for treating cognitive deficits, given the positive effects of its antagonists in a wide range of memory impairment paradigms. Herein, we report on degradation of the

ARYLSULFONAMIDES OF 2-ARYLPYRROLE-3-CARBOXAMIDES FOR THE TREATMENT OF CNS DISORDERS

The inventions relates to novel arylsulfonamides of 2-aryl-2,5-dihydro-7H-pyrrole-3-carboxamide derivatives of general formula (I): A wherein: Ar represent 5-6 membered aromatic/heteroaromatic ring optionally substituted with halogen atoms, an alkyl group substituted with one or more halogen atoms, or C1-C2 alkoxy group; A represents unsubstituted aryl (5-6 membered), biaryl (8-10 membered), heteroaryl (5-6 membered), heteroaryl (8- 10 membered) having 1 or 2 heteroatoms independently selected from the group consisting of N or S, optionally substituted with one or more substituents selected from an alkyl (C1-C3) group, an alkyl (Ci- C3) group substituted with one or more halogen atoms, an alkoxy (C1-C3) group, an alkoxy (C1-C3) group substituted with one or more halogen atoms, cyano; Ri represents alicyclic amines selected from differently substituted azetidine, pyrrolidine, piperidine, azepine, tropane. Compounds of the invention display high affinity for the 5-HT6 receptors and affect receptor constitutive activity. Compounds of the invention are useful for the treatment of cognitive deficits related to neuropsychiatric disorders, dementia associated with neurodegenerative disorders, neuropathic pain, and/or other disorders where modification of the constitutive activity of the 5-HT6 receptor is preferable.

Aryl-heteroaromatic products, compositions comprising them and use

Aryl-heteroaromatic products, compositions comprising them and use. The present invention relates to novel chemical compounds, particularly to novel aryl-heteroaromatic products, to compositions comprising them, and to their use as medicaments, in particu