6953-60-2 Usage
General Description
S-Acetylmercaptosuccinic anhydride is an amine reactive reagent, containing a sulfhydryl group. The anhydride region opens up, when attacked by an amine nucleophile, forming amine linkage. However, during this ring opening reaction, a free carboxylate group is formed rendering the molecule negatively charged. Activity to proteins and conformation of the molecule us affected by the charge reversal.
Check Digit Verification of cas no
The CAS Registry Mumber 6953-60-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,9,5 and 3 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 6953-60:
(6*6)+(5*9)+(4*5)+(3*3)+(2*6)+(1*0)=122
122 % 10 = 2
So 6953-60-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H6O4S/c1-3(7)11-4-2-5(8)10-6(4)9/h4H,2H2,1H3/t4-/m0/s1
6953-60-2Relevant articles and documents
Regioselective ring opening of thiomalic acid anhydrides by carbon nucleophiles. Synthesis and X-ray structure elucidation of novel thiophenone derivatives
Kikionis, Stefanos,McKee, Vickie,Markopoulos, John,Igglessi-Markopoulou, Olga
experimental part, p. 3711 - 3716 (2009/09/05)
Novel and promising thiophenone derivatives were synthesised by regioselective ring opening of activated thiomalic acid anhydrides, with a variety of active methylene nucleophiles via a C-acylation/cyclisation process involving an S-C bond formation. This
