6963-03-7

Basic information

• Product Name: 6-NITRO-4H-1,3-BENZODIOXINE
• Synonyms: 6-NITRO-4H-1,3-BENZODIOXINE
• CAS NO: 6963-03-7
• Molecular Formula: C₈H₇NO₄
• Molecular Weight: 181.15
• Mol File: 6963-03-7.mol

Chemical Properties

• Boiling Point: 339.9°Cat760mmHg
• Flash Point: 179°C
• Appearance: /
• Density: 1.391g/cm³
• Vapor Pressure: 0.000176mmHg at 25°C
• Refractive Index: 1.584
• CAS DataBase Reference: 6-NITRO-4H-1,3-BENZODIOXINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-NITRO-4H-1,3-BENZODIOXINE(6963-03-7)
• EPA Substance Registry System: 6-NITRO-4H-1,3-BENZODIOXINE(6963-03-7)

Safety Data

• Hazardous Substances Data: 6963-03-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
6-NITRO-4H-1,3-BENZODIOXINE is used as a synthetic intermediate for the development of various pharmaceutical compounds. Its unique chemical structure allows it to be a key component in the synthesis of drugs with specific therapeutic properties.
Used in Anti-arthritic Applications:
In the field of anti-arthritic research, 6-NITRO-4H-1,3-BENZODIOXINE has demonstrated potential as an effective agent. It has been shown to exhibit anti-arthritic effects in rats, making it a promising candidate for further research and development in the treatment of arthritis.
Used in Antioxidant Applications:
6-NITRO-4H-1,3-BENZODIOXINE also has antioxidant properties, which can be beneficial in various industries, including pharmaceuticals and cosmetics. Its ability to neutralize free radicals and protect cells from oxidative damage makes it a valuable component in the development of products that promote overall health and well-being.

InChI:InChI=1/C8H7NO4/c10-9(11)7-1-2-8-6(3-7)4-12-5-13-8/h1-3H,4-5H2

Upstream product

• 50-00-0 formaldehyd 
• 39224-61-8 2-hydroxy-5-nitrobenzyl alcohol 
• 100-02-7 4-nitro-phenol 
• 254-27-3 4H-benzo[1,3]dioxine 
• 7697-37-2 nitric acid 
• 64-19-7 acetic acid 
• 7383-11-1 2-aminomethyl-4-nitro-phenol 
• 15454-33-8 chloromethanol 
• 542-88-1 bis(2-chloromethyl)ether 

Downstream Products

• 16607-27-5 6,8-dinitro-4H-benzo[1,3]dioxin 
• 22791-64-6 6-amino-1,3-benzodioxane 
• 254-27-3 4H-benzo[1,3]dioxine 
• 99849-17-9 8-chloromethyl-6-nitro-4H-benzo[1,3]dioxin 
• 22802-61-5 2-Methoxymethyl-4-nitro-phenol 

Relevant articles and documents

Syntheses of 6-Amino-1,3-benzodioxin and Its p-Arylazo-Substituted Calixarenes

The p-arylazo-substituted calixarenes were synthesized by a diazo-coupling reaction between calixarene and the diazonium salt of 6-amino-1,3-benzodioxin.The monoarylazo-, 1,2-diarylazo-, 1,3-diarylazo-, triarylazo-, and tetraarylazo-para-substituted calixarenes were isolated and characterized by spectral methods. 6-Amino-1,3-benzodioxin was prepared by palladium metal reduction of 6-nitro-1,3-benzodioxin.

Oxidative hair dyeing compositions based on 4-aminophenol derivatives and new 4-aminophenol derivatives

Compositions for oxidative dyeing of hair based on 4-aminophenol derivatives of the formula (I): STR1 or their physiologically compatible water soluble salts, wherein R is selected from the group consisting of alkyl groups with from one to four carbon atoms, monohydroxyalkyl groups with from two to four carbon atoms, aminoalkyl groups with from two to four carbon atoms, aminoalkyl groups having amino groups substituted with from one to two alkyl groups having from one to four carbon atoms and dihydroxyalkyl groups with from three to four carbon atoms. New developer substances include 4-amino-2-propoxymethyl phenol, 4-amino-2-isopropoxymethyl phenol and 4-amino-2-(2'-hydroxyethoxymethyl)-phenol. The developer substances of the formula I have physiologically improved properties with equally good dyeing properties as the p-aminophenol used up to now in the red region of the spectrum.

Heterocycles dioxinniques. Nouvelle methode de synthese des benzo (4H) dioxinnes-1,3

The condensation reactions between variously substituted phenols and paraformaldehyde were carried out in the presence of ion exchangers used as catalysts.The control of the hydration rate of the reaction medium afforded the selective formation of the corresponding 4H-benzo-1.3-dioxins.