6965-39-5

Basic information

• Product Name: 2-(4-CHLORO-PHENYL)-N-HYDROXY-ACETAMIDINE
• Synonyms: 2-(4-CHLORO-PHENYL)-N-HYDROXY-ACETAMIDINE;BENZENEETHANIMIDAMIDE,4-CHLORO-N-HYDROXY-
• CAS NO: 6965-39-5
• Molecular Formula: C₈H₉ClN₂O
• Molecular Weight: 184.62
• Product Categories: pharmacetical
• Mol File: 6965-39-5.mol
• Article Data: 24

Chemical Properties

• Boiling Point: 366.8°Cat760mmHg
• Flash Point: 175.7°C
• Appearance: /
• Density: 1.31g/cm³
• CAS DataBase Reference: 2-(4-CHLORO-PHENYL)-N-HYDROXY-ACETAMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-CHLORO-PHENYL)-N-HYDROXY-ACETAMIDINE(6965-39-5)
• EPA Substance Registry System: 2-(4-CHLORO-PHENYL)-N-HYDROXY-ACETAMIDINE(6965-39-5)

Safety Data

• Hazardous Substances Data: 6965-39-5(Hazardous Substances Data)

Usage

General Description

2-(4-Chloro-phenyl)-N-hydroxyacetamidine is a chemical compound with the molecular formula C8H8ClN3O. It is a derivative of acetamidine and features a chlorine-substituted phenyl group. 2-(4-CHLORO-PHENYL)-N-HYDROXY-ACETAMIDINE is a potential intermediate in the synthesis of pharmaceuticals and other organic compounds. It may also have applications in the field of organic chemistry and drug development, given its unique structure and potential reactivity. Further research may be necessary to fully understand the potential uses and properties of 2-(4-Chloro-phenyl)-N-hydroxyacetamidine.

Upstream product

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Downstream Products

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• 1429214-07-2 6-((3-(4-chlorobenzyl)-1,2,4-oxadiazol-5-yl)methoxy)-3,4-dihydroquinolin-2(1H)-one 
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• 1041005-72-4 3-(4-chlorobenzyl)-N-isopropyl-1,2,4-oxadiazol-5-amine 
• 1041005-80-4 3-(4-chlorobenzyl)-N-cyclohexyl-1,2,4-oxadiazol-5-amine 

Relevant articles and documents

Novel O-acylated amidoximes and substituted 1,2,4-oxadiazoles synthesised from (+)-ketopinic acid possessing potent virus-inhibiting activity against phylogenetically distinct influenza A viruses

This article describes the synthesis and antiviral activity evaluation of new substituted 1,2,4-oxadiazoles containing a bicyclic substituent at position 5 of the heterocycle and O-acylated amidoximes as precursors for their synthesis. New compounds were

Pharmacophore requirements for HIV-1 reverse transcriptase inhibitors that selectively “Freeze” the pre-translocated complex during the polymerization catalytic cycle

Reverse transcriptase (RT) is responsible for replicating the HIV-1 genome and is a validated therapeutic target for the treatment of HIV infections. During each cycle of the RT-catalyzed DNA polymerization process, inorganic pyrophosphate is released as the by-product of nucleotide incorporation. Small molecules were identified that act as bioisosteres of pyrophosphate and can selectively freeze the catalytic cycle of HIV-1 RT at the pre-translocated stage of the DNA- or RNA-template-primer-enzyme complex.

N-hydroxy-substituted 2-aryl acetamide analogs: A novel class of HIV-1 integrase inhibitors

An in silico method has been used to discover N-hydroxy-substituted 2-aryl acetamide analogs as a new class of HIV-1 integrase inhibitors. Based on the molecular requirements of the binding pocket of catalytic active site, two molecules (compounds 2 and 4