69661-83-2Relevant articles and documents
Iron-catalyzed ferrocenylmethanol OH substitution by S, N, P, and C nucleophiles
Mazzoni, Rita,Salmi, Mauro,Zacchini, Stefano,Zanotti, Valerio
, p. 3710 - 3718 (2013/07/26)
The iron complex [Fp][OTf] {Fp+ = [Fe(CO)2(Cp)] +, OTf- = SO3CF3-} is an efficient catalyst for the direct substitution of the OH group in ferrocenylmethanol [Fc-CH2OH] by thiols, aromatic amines, diphenylphosphane, and carbon nucleophiles (furan, pyrrole, and indole). This approach offers a convenient route to ferrocenes containing side chains with different functional groups. The advantages of the method are associated with the use of a catalyst based on iron, which is a nontoxic and readily available transition metal, and in the direct OH substitution, which produces water as the only byproduct. Direct substitution of the OH group in ferrocenylmethanol by S, N, P, and C nucleophiles containing an active hydrogen atom (thiols, aromatic amines, diphenylphosphane, furan, pyrrole, indole) can be accomplished by use of the iron catalyst [Fe(CO)2(Cp)][OTf] (Cp = cyclopentadienyl, OTf = SO3CF3). Copyright
The reactions of α-phenyl- and α-ferrocenylcarbinols with diiron nonacarbonyl
Bankston, D.
, p. 129 - 138 (2007/10/02)
Diiron nonacarbonyl oxidized a series of α-phenylcarbinols to their corresponding aldehydes and ketones.In addition, this resagent converted 4-methoxybenzyl alcohol to 4-methoxybenzyl ether, albeit in low yield.Under the same reaction conditions, oxidation was a minor with a group of α-ferrocenylcarbinols as ether synthesis was the major reaction with those substrates which could not dehydrate; however, stereoselective olefin synthesis predominated when elimination was possible.
