69691-19-6

Basic information

• Product Name: Methyl 2-Methyl-4-hexynate
• Synonyms: Methyl 2-Methyl-4-hexynate;methyl 2-methylhex-4-ynoate
• CAS NO: 69691-19-6
• Molecular Formula: C8H12O2
• Molecular Weight: 140.17968
• Mol File: 69691-19-6.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Methyl 2-Methyl-4-hexynate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 2-Methyl-4-hexynate(69691-19-6)
• EPA Substance Registry System: Methyl 2-Methyl-4-hexynate(69691-19-6)

Safety Data

• Hazardous Substances Data: 69691-19-6(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 802294-64-0 propionic acid 
• 3355-28-0 1-Bromo-2-butyne 
• 51577-97-0 2-methylhex-4-ynoic acid 
• 74-88-4 methyl iodide 
• 186581-53-3 diazomethane 

Downstream Products

• 1035094-10-0 (E)-2,2,3,3-d4-5-((3aS,4R,5R,6aS)-5-hydroxy-4-((3S,E)-3-hydroxy-4-methyloct-1-en-6-ynyl)hexahydropentalen-2(1H)-ylidene)pentanoic acid 
• 88430-50-6 (±)-(1R,2R,3aS,8bS)-2,3,3a,8b-tetrahydro-2-hydroxy-1-[(E)-(3S,4RS)-3-hydroxy-4-methyl-1-octen-6-ynyl]-1H-cyclopenta[b]-benzofuran-5-butanoic acid 

Relevant articles and documents

PROSTACYCLIN DERIVATIVES

This invention relates to novel prostacyclin derivatives and acceptable salts thereof. The invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions benefic

Synthesis of 5,6,7-trinor-4,8-inter-m-phenylene PGI2 and Beraprost

We have disclosed a new class of stable PGI2 analogue, 5,6,7-trinor- 4,8-inter-m-phenylene PGI2 which has a phenyl ether moiety instead of enol- ether skeleton in PGI2. The m-phenylene PGI2 and its derivative (Betaprost) were synthesized via dihydrocyclopenta[b]benzofuran derivatives as key intermediates by ortho-selective metal-halogen exchange reaction with Grignard reagents and subsequent copper-catalyzed cyclization. The ω-side chains were introduced by stereoselective epoxide formation or Prins reaction.