69696-35-1

Usage

Uses

Used in Pharmaceutical Industry:
5-Bromo-4-chloro-2,6-dimethylpyrimidine is used as a pharmaceutical intermediate for the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs.
Used in Agricultural Chemicals:
In the agricultural sector, 5-Bromo-4-chloro-2,6-dimethylpyrimidine serves as an intermediate in the production of agricultural chemicals, contributing to the development of effective pest control solutions and other agrochemical products.
Used in Dyes and Pigments Manufacturing:
5-Bromo-4-chloro-2,6-dimethylpyrimidine is also employed in the manufacturing of dyes and pigments, where its chemical properties enable the creation of a wide range of colorants for various applications.
Safety Measures:
Due to the potential environmental and health hazards associated with 5-Bromo-4-chloro-2,6-dimethylpyrimidine, it is crucial to follow appropriate safety measures when handling and using this chemical compound. This includes proper storage, handling, and disposal protocols to minimize risks.

Upstream product

• 6622-92-0 4-hydroxy 2,6-dimethylpyrimidine 
• 858269-28-0 5-bromo-2,6-dimethylpyrimidin-4-ol 
• 858269-28-0 5-bromo-2,6-dimethyl-3H-pyrimidin-4-one 
• 6622-92-0 2,6-dimethyl-1H-pyrimidin-4-one 

Downstream Products

• 127588-24-3 4-chloro-2,6-dimethyl-5-phenylpyrimidine 
• 38202-09-4 2,4-dimethyl-5,6-diphenylpyrimidine 
• 69696-37-3 5-bromo-2,4-dimethylpyrimidine 
• 1445787-42-7 3-((3-carbamoyl-7-(2,4-dimethylpyrimidin-5-yl)quinolin-4-yl)amino)-5-isopropoxybenzoic acid 
• 1445790-87-3 methyl 3-((3-carbamoyl-7-(2,4-dimethylpyrimidin-5-yl)quinolin-4-yl)amino)-5-isopropoxybenzoic acid 
• 1445787-44-9 3-((7-(2,4-dimethylpyrimidin-5-yl)-3-sulfamoylquinolin-4-yl)amino)-5-isopropoxybenzoic acid 
• 1445790-91-9 methyl 3-((7-(2,4-dimethylpyrimidin-5-yl)-3-sulfamoylquinolin-4-yl)amino)-5-isopropoxybenzoate 
• 1445787-52-9 3-((3-carbamoyl-7-(2,4-dimethylpyrimidin-5-yl)-8-fluoroquinolin-4-yl)amino)-5-cyclopentylbenzoic acid 
• 1445790-97-5 methyl 3-((3-carbamoyl-7-(2,4-dimethylpyrimidin-5-yl)-8-fluoroquinolin-4-yl)amino)-5-cyclopentylbenzate 
• 1951411-46-3 2,4-dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine 

Relevant academic research and scientific papers

TRIAZOLOPYRIDINE COMPOUNDS AND USES THEREOF

A compound of Formula (IA), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating a PRC2-mediated disease or disorder: wherein A, R6, R7 and R8 are as defined herein.

IMIDAZOPYRIMIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF CANCER

A compound of Formula (IA), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating a PRC2-mediated disease or disorder: wherein A, R3, R4, R6, and R7 are as defined herein.

TRIAZOLOPYRIMIDINE COMPOUNDS AND USES THEREOF

A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating a PRC2-mediated disease or disorder: wherein R1, R2, R3, R4, R5, and n are as defined herein.

CHEMICAL COMPOUNDS

The invention is directed to substituted quinoline derivatives. Specifically, the invention is directed to compounds according to Formula (I): wherein R1, R2, R3; R4; and R5 are defined herein. The compounds of the invention are inhibitors of lactate dehydrogenase A and can be useful in the treatment of cancer and diseases associated with tumor cell metabolism, such as cancer, and more specifically cancers of the breast, colon, prostate and lung. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting lactate dehydrogenase A activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.