697-64-3

Basic information

• Product Name: (R)-(-)-1-INDANOL
• Synonyms: (R)-(-)-1-INDANOL;R(-)-1-HYDROXYINDAN;(1R)-Indan-1-ol;(1R)-Indan-1α-ol;(R)-2,3-Dihydro-1H-indene-1-ol;(R)-2,3-Dihydro-1H-indene-1α-ol;(R)-Indan-1-ol;(R)-2,3-dihydro-1H-inden-1-ol
• CAS NO: 697-64-3
• Molecular Formula: C₉H₁₀O
• Molecular Weight: 134.18
• Mol File: 697-64-3.mol
• Article Data: 232

Chemical Properties

• Melting Point: 72-73 °C(lit.)
• Boiling Point: 255.1 °C at 760 mmHg
• Flash Point: 89.2 °C
• Appearance: /
• Density: 1.161 g/cm³
• Vapor Pressure: 0.00859mmHg at 25°C
• Refractive Index: 1.609
• Storage Temp.: 2-8°C
• BRN: 4350388
• CAS DataBase Reference: (R)-(-)-1-INDANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(-)-1-INDANOL(697-64-3)
• EPA Substance Registry System: (R)-(-)-1-INDANOL(697-64-3)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 697-64-3(Hazardous Substances Data)

Usage

Uses

R-?(-?)?-?1-?Indanol is a building block used in pharmaceutical synthesis such as in the preparation of meropenem prodrugs for drug-resistant tuberculosis.

InChI:InChI=1/C9H10O/c10-9-6-5-7-3-1-2-4-8(7)9/h1-4,9-10H,5-6H2/t9-/m1/s1

Upstream product

• 95-13-6 1-indene 
• 158529-97-6 (R)-1-indanyl butyrate 
• 26452-98-2 2,3-dihydro-1H-inden-1-yl-acetate 
• 496-11-7 INDANE 
• 1338369-41-7 C₂₇H₂₄OSi 
• 1313511-75-9 C₁₅H₂₄OSi 
• 1313511-76-0 C₁₇H₂₀OSi 
• 1313511-77-1 C₂₂H₂₂OSi 
• 76-86-8 Triphenylsilyl chloride 
• 6351-10-6 1-Indanol 
• 73951-60-7 Acetic acid (1S,2S)-2-chloro-indan-1-yl ester 
• 108-22-5 Isopropenyl acetate 
• 83-33-0 inden-1-one 
• 109129-77-3 succinic acid mono-((R)-indan-1-yl ester) 

Downstream Products

• 83-33-0 inden-1-one 
• 691899-87-3 (S)-4-[(2,3-dihydro-1H-inden-1-yl)oxy]benzenepropanoic acid 
• 1292296-64-0 methyl-p-tolylthiocarbamic acid (S)-indan-1-yl ester 
• 6351-10-6 1-Indanol 
• 691899-72-6 methyl (S)-4-[(2,3-dihydro-1H-inden-1-yl)oxy]benzenepropanoate 
• 68000-22-6 (S)-2,3-dihydro-1H-indene-1-carboxylic acid 

Relevant articles and documents

Designer Outer Membrane Protein Facilitates Uptake of Decoy Molecules into a Cytochrome P450BM3-Based Whole-Cell Biocatalyst

We report an OmpF loop deletion mutant, which improves the cellular uptake of external additives into an Escherichia coli whole-cell biocatalyst. Through co-expression of the OmpF mutant with wild-type P450BM3 in the presence of decoy molecules, the yield

An Engineered Cholesterol Oxidase Catalyses Enantioselective Oxidation of Non-steroidal Secondary Alcohols

The enantioselective oxidation of 2° alcohols to ketones is an important reaction in synthetic chemistry, especially if it can be achieved using O2-driven alcohol oxidases under mild reaction conditions. However to date, oxidation of secondary alcohols using alcohol oxidases has focused on activated benzylic or allylic substrates, with unactivated secondary alcohols showing poor activity. Here we show that cholesterol oxidase (EC 1.1.3.6) could be engineered for activity towards a range of aliphatic, cyclic, acyclic, allylic and benzylic secondary alcohols. Additionally, since the variants demonstrated high (S)-selectivity, deracemisation reactions were performed in the presence of ammonia borane to obtain enantiopure (R)-alcohols.

Chiral Yolk-Shell MOF as an Efficient Nanoreactor for Asymmetric Catalysis in Organic-Aqueous Two-Phase System

It remains a great challenge to introduce large and efficient homogeneous asymmetric catalysts into MOFs and other microporous materials as well as retain their degrees of freedom. Herein, a new heterogeneous strategy of homogeneous chiral catalysts is proposed, that is, to construct a yolk-shell MOFs-confined, large-size, and highly efficient homogeneous chiral catalyst, which can be used as a nanoreactor for asymmetric catalytic reactions.