69706-65-6

Upstream product

• 125160-86-3 6-hydroxy-1-phenylhexane-1,3-dione 
• 107-04-0 1-Bromo-2-chloroethane 
• 93-91-4 1-phenylbutan-1,3-dione 
• 7721-58-6 3-methylamino-1-phenylbut-2-en-1-one 
• 98-86-2 acetophenone 

Downstream Products

• 69706-69-0 (Z)-6-Hydroxy-3-(2-{4-hydroxy-1-[2-oxo-2-phenyl-eth-(Z)-ylidene]-butylamino}-ethylamino)-1-phenyl-hex-2-en-1-one 
• 866216-58-2 2-bromo-2-(dihydrofuran-2(3H)-ylidene)-1-phenylethanone 
• 866216-63-9 (Z)-2-bromo-2-[3-bromo-4,5-dihydrofuran-2(3H)-ylidene]-1-phenylethanone 
• 866216-69-5 2-(dihydro-furan-2(3H)-ylidene)-2-(2-methoxy-phenyl)-1-phenyl-ethanone 
• 69706-72-5 (Z)-3-Benzylamino-6-hydroxy-1-phenyl-hex-2-en-1-one 

Relevant academic research and scientific papers

Synthesis of 4-(3-hydroxyalkyl)pyrimidines by ring transformation reactions of 2-alkylidenetetrahydrofurans with amidines

Domino reactions of amidines with 2-alkylidenetetrahydrofurans, prepared by cyclization of 1,3-dicarbonyl dianions or 1,3-bis-silyl enol ethers with various dielectrophiles, provided an efficient access to 4-(3-hydroxyalkyl)pyrimidines.

Synthesis of benzofurans with remote bromide functionality by domino "ring-cleavage-deprotection-cyclization" reactions of 2-alkylidenetetrahydrofurans with boron tribromide

Bromination and subsequent Suzuki reactions of 2- alkylidenetetrahydrofurans, readily available by [3+2] cyclizations, afforded 1′-(2″-methoxyphenyl)-2-alkylidenetetrahydrofurans. Treatment of the latter with boron tribromide and subsequent addition of wa

Chemoselective, Regioselective, and E/Z-Diastereoselective Synthesis of 2-Alkylidenetetrahydrofurans by Sequential Reactions of Ambident Dianions and Monoanions

A number of novel β-ketoesters were prepared by regioselective alkylation reactions of simple β-ketoester dianions. The cyclization of the dianions of these 1,3-dicarbonyl derivatives with 1-bromo-2-chloroethane afforded a variety of 2-alkylidenetetrahydr

Reaction of Dianions of Acyclic β-Enamino Ketones with Electrophiles. Part 2. Oxiranes: Synthesis of γ'- and ε-Hydroxy-β-enamino Ketones and of α-Tetrahydrofurylidene Ketones.

β-Monoalkylamino-α,β-unsaturated ketones can be regioselectively dimetallated either at the α'- or in the γ-positions.The reaction of the resulting dianions with oxiranes proceeds in good to high yields affording the corresponding hydroxyalkyl derivatives

Synthetic applications of 6-hydroxy-1-arylhexane-1,3-diones

Facile synthesis of (E)-2-(aroylmethylene)tetrahydrofurans (17-19), 3-aryl-5-(γ-hydroxypropyl)isoxazoles (5-7), 6-hydroxy-1-aryl-3-substitutedaminohex-2-ene-1-ones (14-16), 3-cyano-6-hydroxy-1-arylhex-2-ene-1-ones (23-25) and one pot synthesis of 2-(α-phe