697235-58-8Relevant articles and documents
Precursor-directed combinatorial biosynthesis of cinnamoyl, dihydrocinnamoyl, and benzoyl anthranilates in saccharomyces cerevisiae
Eudes, Aymerick,Benites, Veronica Teixeira,Wang, George,Baidoo, Edward E.K.,Lee, Taek Soon,Keasling, Jay D.,Loqué, Dominique
, (2015/11/24)
Biological synthesis of pharmaceuticals and biochemicals offers an environmentally friendly alternative to conventional chemical synthesis. These alternative methods require the design of metabolic pathways and the identification of enzymes exhibiting ade
Exploration of the chemical space of novel naphthalene-sulfonamide and anthranilic acid-based inhibitors of penicillin-binding proteins
Sosic, Izidor,Turk, Samo,Sinreih, Masa,Trost, Nusa,Verlaine, Olivier,Amoroso, Ana,Zervosen, Astrid,Luxen, Andre,Joris, Bernard,Gobec, Stanislav
, p. 380 - 388 (2012/09/05)
Penicillin-binding proteins are a well established, validated and still a very promising target for the design and development of new antibacterial agents. Based on our previous discovery of several noncovalent small-molecule inhibitor hits for resistant