6973-08-6

Basic information

• Product Name: 3-AMINO-4-METHOXYBENZENESULFONAMIDE
• Synonyms: Benzenesulfonamide, 3-amino-4-methoxy-;Einecs 230-215-7;Metanilamide, 4-methoxy-;Nsc 36970
• CAS NO: 6973-08-6
• Molecular Formula: C₇H₁₀N₂O₃S
• Molecular Weight: 202.23
• EINECS: 230-215-7
• Mol File: 6973-08-6.mol
• Article Data: 6

Chemical Properties

• Melting Point: 142-142.5 °C
• Boiling Point: 429.5°C at 760 mmHg
• Flash Point: 213.6°C
• Appearance: /
• Density: 1.397g/cm³
• Vapor Pressure: 1.39E-07mmHg at 25°C
• Refractive Index: 1.595
• PKA: 10.52±0.60(Predicted)
• CAS DataBase Reference: 3-AMINO-4-METHOXYBENZENESULFONAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-4-METHOXYBENZENESULFONAMIDE(6973-08-6)
• EPA Substance Registry System: 3-AMINO-4-METHOXYBENZENESULFONAMIDE(6973-08-6)

Safety Data

• Hazardous Substances Data: 6973-08-6(Hazardous Substances Data)

Usage

General Description

3-AMINO-4-METHOXYBENZENESULFONAMIDE is a chemical compound with the molecular formula C7H9N1O3S1. It is an amino-benzenesulfonamide derivative, containing an amine group and a methoxy group attached to the benzene ring. 3-AMINO-4-METHOXYBENZENESULFONAMIDE is commonly used as a building block in the synthesis of pharmaceuticals and organic dyes. It has been studied for its potential use in treating various medical conditions, including cancer and bacterial infections. 3-AMINO-4-METHOXYBENZENESULFONAMIDE is typically stored and handled as a solid powder, and should be used with caution due to its potential hazardous nature.

InChI:InChI=1/C7H10N2O3S/c1-12-7-3-2-5(4-6(7)8)13(9,10)11/h2-4H,8H2,1H3,(H2,9,10,11)

Upstream product

• 1129-26-6 4-methoxybenzene sulfonamide 
• 498-74-8 3-Amino-4-methoxy benzene sulphonylfluoride 
• 93-26-5 2-methoxyacetanilide 
• 85605-29-4 3-acetylamino-4-methoxy-benzenesulfonic acid amide 
• 3746-67-6 3-(acetylamino)-4-methoxybenzensulfonyl chloride 

Downstream Products

• 15939-73-8 5-(2-Methoxy-5-sulfamoylphenylazo)-6-hydroxychrysen 
• 444731-17-3 4-methoxy-3-({4-[(3-methyl-1H-indazol-6-yl)amino]-2-pyrimidinyl}amino)benzenesulfonamide 
• 1620843-79-9 3-[[4-[N-(2,3-dimethyl-2H-indazol-6-yl)-N-methylamino]-6,7-dihydro-5H-cyclopenta[d]pyrimidin-2-yl]amino]-4-methoxy-benzenesulfonamide 
• 1377582-38-1 3-Isothiocyanato-4-methoxy-benzenesulfonamide 
• 1377582-39-2 4-methoxy-3-thioureido-benzenesulfonamide 
• 27320-80-5 6-Sulfamoyl-2H-1,4-benzoxazin-3-on 
• 42792-26-7 (2-Methoxy-5-sulfamoyl)-(1-ethyl-2-pyrrolidinyl)acetanilid 

Relevant articles and documents

Aromatic C-H amination in hexafluoroisopropanol

We report a direct radical aromatic amination reaction that provides unprotected anilines with an improvement in the substrate scope compared to prior art. Hydrogen bonding by the solvent hexafluoroisopropanol to anions of cationic species is responsible for increased reactivity and can rationalize the enhancement in substrate scope. Our findings may have bearings on radical additions to arenes for direct C-H functionalization in general.

PYRIDYL-THIAZOLYL INHIBITORS OF PRO-MATRIX METALLOPROTEINASE ACTIVATION

This invention relates to thiazole I and its therapeutic and prophylactic uses, wherein the variables Rz, Q, J, R1, R3, R5, and R6 are defined in the specification. Disorders treated and/or prevented include rheumatoid arthritis.

Azo reactive dyestuffs having an aryl-triazinyl-aryl diazo component

Optionally metallized azo dyestuffs which in the form of the free acid correspond to the formula STR1 wherein K is the radical of a benzene, naphthalene, pyrazolone, pyridone, pyrimidone, acetoacetic acid arylide or aminopyrazole coupling component; A is a non-ionic substituent; X is STR2 wherein W is a direct bond or a bridge member to a C atom of the benzene or naphthalene nucleus or the coupling component K; R is hydrogen or C1 -C4 -alkyl; B is a direct bond or a bridge member, especially -CO- or -SO2 -, to a C atom of Q; Q is a reactive radical; m is 0, 1 or 2; n is 0, 1 or 2; p is 0 or 1; q is 0, 1 or 2; and r is 0 or 1; and their use for the dyeing and printing of natural and regenerated cellulose fibre materials such as cotton and rayon, as well as natural and synthetic polyamide fibre materials, for example those of wool, silk, poly-ε-caprolactam or polycondensate of hexamethylene-diamine and adipic acid. The dyeings obtained, espeically those on cotton and rayon, are distinguished by good fastness properties, especially fastness to wet processing and to light.